BRIC Small Animal Imaging Facility Imaging Seminar: TriTom – a multimodal platform for in vivo 3D imaging of small animals

Date & Time: Thursday, September 26^th, 1:00 -2:00 PM, followed by online demo and Q&A 2:00-3:00 PM
Location: Marsico Hall, Room 2004

Title: TriTom – a multimodal platform for in vivo 3D imaging of small animals
Speaker: Dr. Sergey Ermilov, PhotoSound, Inc.

Abstract:

 The TriTom platform is designed for in vivo molecular, physiological, and anatomical imaging of preclinical murine models. It employs co-registered photoacoustic and fluorescence imaging channels enabling high-fidelity visualization of regions that either absorb light or fluoresce at imaging depths up to 20-40 mm. A typical 36-sec long TriTom 3D scan interrogates a large volume of tissue (> 25 cm3) producing molecular maps accurately registered to 3D anatomy (high-resolution blood circulatory system, internal organs, and skin). TriTom visualizes oxyhemoglobin, deoxyhemoglobin, and melanin without a need to use contrast agents, enabling spatially-resolved longitudinal assessment of vascular morphology and density, blood oxygenation, ischemia, tumor growth and metastasis. TriTom also provides quantitative in vivo imaging for a wide range of nanoparticles and molecular probes that absorb light in 460 nm – 1320 nm spectral range, and for fluorescent molecular probes with excitation between 460 nm and 800 nm, enabling applications in toxicology and targeted molecular imaging. With powerful and unique in vivo imaging capabilities, TriTom presents new ways to study live small animal models in a number of preclinical applications including cancer, toxicology, tissue engineering and regeneration, developmental biology, neuroscience, as well as in the development of drugs, therapies, optical and fluorescent molecular probes.

More information: https://www.med.unc.edu/bric/small-animal-imaging/small-animal-imaging-seminar/

You are welcome to forward the email to anyone who might be interested.

(Coffee and snacks will be served)