News

Jason Whitmire, PhD, Associate Professor in the Department of Genetics and Stanley Lemon, MD, Professor in the Department of Medicine, were senior authors on a paper titled “MAVS-dependent host species range and pathogenicity of human hepatitis A virus” published in the journal Science. The paper, published in the 15 SEP...

Charles Perou, PhD, Professor of Genetics and Pathology and Laboratory Medicine and the May Goldman Shaw Distinguished Professor of Molecular Oncology was corresponding author of a study that focused on finding possible drug targets in triple-negative breast cancers. The paper, titled “Genomic Profiling of Murine Mammary Tumors Identifies Potential Personalized...

Praveen Sethupathy, PhD, an Assistant Professor in the Department of Genetics, was corresponding author of a study that investigated the role of microRNAs in the mediation of intestinal epithelial cell (IEC) homeostasis. The paper titled “miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad...

This project will focus on identifying genetic, regulatory activity, and gene expression changes that significantly contribute to IBD at molecular and clinical levels. Terry Furey, PhD, Associate Professor of Genetics and Biology and Shehzad Sheikh, MD, PhD, Assistant Professor of Medicine and Genetics and Member of the Multidisciplinary Center for...

This study will focus on development of a computational framework for storing, sharing and analyzing three-dimensional micron resolution images in fluorescently-labeled brain samples, with a specific focus on brain structure deficits in an autism mouse model. Jason Stein, PhD, Assistant Professor of Genetics with a joint appointment in the UNC...

The research in Dr. Tarantino’s laboratory is focused on identification and characterization of genes that influence behavior. In particular, they study mouse models of addiction, anxiety, stress and depression-like behaviors. Dr. Tarantino will have a primary appointment in Genetics, secondary appointment in Psychiatry and a joint appointment in the School...

The article reviews progress in the microRNA field over the past decade, and details findings in pre-clinical studies that have demonstrated that pharmacologic manipulation of microRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes. Praveen Sethupathy, PhD, Assistant Professor in...

Karen Mohlke, Chuck Perou, Pat Sullivan and Jenny Ting have been named to the list of 2015 Highly Cited Researchers. Karen Mohlke, Chuck Perou, Pat Sullivan and Jenny Ting have been named to the list of 2015 Highly Cited Researchers. The 3000 researchers highlighted in 2015 represent the top one...

Jonathan Berg, MD, PhD, a UNC Lineberger member and an assistant professor in the UNC School of Medicine Department of Genetics, was corresponding author of a study that investigated the frequency of pathogenic germline variants in hereditary cancer susceptibility genes in cancer patients undergoing tumor-germline sequencing. ~From the UNC LIneberger...

The study will focus on genetic mechanisms underlying blood cell traits in multi-ethnic cohorts, in particular admixed, under-represented U.S. minority populations such as African Americans and Hispanics/Latinos. Yun Li, PhD, Associate Professor of Genetics, Biostatistics and Computer Science (adjunct) has been awarded an R01 from the National Heart, Lung, and...