News

Jim was one of four discussants on NPR’s “On Point” and coauthor of an editorial in JAMA The “On Point” discussion, related to President Obama’s announcement regarding the Precision Medicine Initiative, is available as a podcast. In the JAMA Viewpoint article, Jim and Michael Watson of the ACMG Foundation for...

The title of the paper is “Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.” Sara is a BCB graduate student who is co-mentored by Praveen Sethupathy and Stan Lemon (Department of Medicine). In this study, Selitsky et al. identify for the first...

Matt Weiser, a graduate student in Terry’s lab, is first author on the paper, entitled “Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations.” Standard eQTL mapping methods carry significant multiple testing burdens, limiting their ability to detect eQTL distal to the affected gene....

Shawn and Eric Miska at the University of Cambridge are senior authors on the paper, and Shawn’s former postdoc, Aisa Sakaguchi, and former graduate student, Matt Simon, as co-first authors with Peter Sarkies from Dr. Miska’s lab. This study establishes a role for small RNAs in promoting transgenerational fertility via...

Fernando will serve a three-year term beginning January 1, 2015. See the official announcement on the GSA web site. The GSA is the professional membership organization for scientific researchers and educators in the field of genetics, with over 5,000 members. Society members work to advance knowledge in the basic mechanisms...

Yun Li, Karen Mohlke, and Chuck Perou are among the top 1% most cited world researchers in their subject fields for 2014. Thomson Reuters has listed Yun and Karen among the most highly cited in Molecular Biology & Genetics and Chuck in Clinical Medicine. To see the complete list and...

Evans and Perou are quoted regarding the risks of reporting germline mutations in numerous genes implicated in rare forms of hereditary predispositions to breast cancer. Chuck points out that there are probably 10 – 100 genes in addition to BRCA1 and BRCA2 that may contribute to breast cancer susceptibility. Both...

The article discusses three reports on DNA variants in the human genome that affect gene regulation epigenetically, via sequence-specific binding-affinity of transcription factors.

Dr. Sharpless succeeds H. Shelton “Shelley” Earp, MD, as center director effective January 1, 2014. William Roper, MD, MPH, Dean of the School of Medicine, Vice Chancellor for Medical Affairs, and CEO of University of North Carolina Health Care System, announces the appointment of Norman “Ned” Sharpless, MD, as director...

In collaboration with groups at three other institutions, they identified different miRNAs that are critical “regulatory hubs” in the immune response to the parasites Leishmania major and Schistosoma mansoni. Samir and Praveen share first authorship with Isobel Okoye at the National Institute for Medical Research in London. In addition to...