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Hospitalizations for Pediatric Opioid Use Disorders: Exploring Racial Disparities among US regions

Exposure to prescription opioids in the pediatric population is an important public health concern. Opioid hospitalizations among US children and adolescents have doubled in the last decade. There is an urgent need to better characterize the opioid epidemic in all pediatric populations, across different racial groups and regions in the United States. However, research on pediatri … Read more

Role of Rehabilitation in Concussion Management: A Randomized, Controlled Trial

We propose a randomized clinical trial to yield preliminary data on the added benefits of active rehabilitation during recovery after sport-related concussion in professional and amateur athletes. This trial marks an international collaborative effort involving the NFL, CFL, New Zealand Rugby, American Hockey League, and academic researchers in the United States. Specific Aims: T … Read more

Advancing Social-communication and Play (ASAP): An Intervention Program for Preschoolers with Autism

The primary aim of the Advancing Social-communication And Play (ASAP) intervention is to promote the social-communication and play skills of preschoolers with autism spectrum disorder (ASD) being served in public preschool programs. The ASAP grant project was a four-year, multisite study funded by the Institute of Education Sciences (IES), U.S. Department of Education was to exam … Read more

Critical Thinking in Radiologic Science Education

The purpose of this mixed method study is to examine the critical thinking disposition and perceptions of Radiologic Science students through the use of a standardized assessment and journaling exercises. The Radiologic Science student’s critical thinking deposition was assessed using the California Critical Thinking Deposition Inventory to determine the willingness and ability o … Read more

Promoting ASAP Collaboration through Technology (PACT): An Intervention Modification to Enhance Home-School Collaboration

The overall purpose of this Goal 2: Development and Innovation project is to enhance the existing Advancing Social-communication and Play (ASAP) intervention through development of a technologically supported system of home-school collaboration. ASAP was originally designed as a classroom-based intervention, in which the educational teams serving preschool-aged children with auti … Read more

Chronic Kidney Disease in Children (CKiD)

This is a multisite study where the primary goal of this project is to investigate the growth, neurocognitive functioning, and disease progression of children with mild to moderate CKD. This is the 12th year of the study.

Written Language Problems in MIddle School Students: A randomized Trial of thE SRSD Approach Using a Tier 2 Intervention Model

RFA Goal: Efficacy and Replication Purpose: The primary purpose of this project is to establish a stronger scientific foundation for educational practice within the writing domain by utilizing recent advances in cognitive science to examine: (1) the impact of the evidence-based Self-Director Strategy Development (SRSD) model on the written expression of middle school children at- … Read more

Executive Function in Pediatric Hypertension

The goal of this multisite study is to investigate the relationship between primary hypertension and executive function as a novel, emerging target of hypertensive damage in children.

Improving sweat testing performance: a multi-center collaborative initiative towards earlier diagnosis of infants with CF and positive CF newborn screening tests

We aim to reduce sweat testing quantity not sufficient (QNS) rates in infants who are referred to Cystic Fibrosis Foundation Accredited Care Centers for follow-up testing after a positive newborn screening (NBS) test. It is important to do this now because there is evidence of both high QNS rates at some centers. Additionally a significant percentage of infants diagnosed with CF … Read more

North Carolina Child Development Survey Cohort 2 (FYI 3.1)

Autism Spectrum Disorder (ASD) is not formally diagnosed before a child is 2-3 years old, but research has identified a wide array of atypical behaviors that can be seen in infants who will eventually receive a diagnosis. We developed a parent-report survey called the First Year Inventory to identify these pre-diagnostic behaviors in 1-year-olds, collected a large sample of norma … Read more