Author Archives: Jason Mock
Comparison of Different Methods of Initiating Lung Inflammation and the Sex-Specific Effects on Inflammatory Parameters
Our manuscript examining lung Inflammation and the sex-specific effects on inflammatory parameters has been accepted in the American Journal of Physiology Lung Cellular and Molecular Physiology.
Bronchoalveolar Tregs are associated with duration of mechanical ventilation in acute respiratory distress syndrome
Dustin Norton’s Alveolar Kinetics in ARDS (AKA) Study has been published in the Journal of Translational Medicine.
COVID-19: Clean up on IL-6
A letter to the editor about the uncertainties of anti-IL6 therapy in COVID-19.
Repair of the Lung by Regulatory T Cells
An editorial on our recent publication in the American Journal of Respiratory Cell and Molecular Biology https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2020-0260ED
Impact of Regulatory T Cells on Type 2 Alveolar Epithelial Cell Transcriptomes during Resolution of Acute Lung Injury and Contributions of IFN-γ
Our publication studying the effects of Foxp3+ regulatory T cells (Tregs) on type 2 alveolar epithelial cells during acute lung injury. https://www.atsjournals.org/doi/full/10.1165/rcmb.2019-0399OC
Effects of IFN-γ on immune cell kinetics during the resolution of acute lung injury
Our publication studying the role of IFN-γ during resolution of acute lung injury. https://physoc.onlinelibrary.wiley.com/doi/full/10.14814/phy2.14368
Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI
Data from our laboratory demonstrate that Tregs isolated from lungs during the resolving phase of lung injury change their expression of many genes, compared to Tregs isolated from uninjured control lungs. These differences highlight the complexity of Treg function in the resolution and repair of lung injury. https://insight.jci.org/articles/view/124958