Category: Research News
PROMOTER Study Aims to Advance Translational Research in Esophageal Diseases
Researchers from the University of North Carolina and North Carolina State University aim to use a pig-based model to study esophageal diseases, a field where scientific understanding remains limited. Researchers use large animal models to help with therapy development, testing and translation. However, fully defined models of digestive diseases are still scarce. Within this fiel … Read more
UNC Joins Phase 3 CATT1 Trial Investigating Cadisegliatin as Adjunctive Therapy for Type 1 Diabetes
The University of North Carolina will serve as a study site for the vTv Therapeutics Inc. CATT1 Phase 3 trial investigating cadisegliatin as an adjunctive treatment to insulin in adults with type 1 diabetes (T1D). Cadisegliatin is a potential first-in-class, oral, liver-selective glucokinase activator for T1D that has been granted Breakthrough Therapy designation by the U.S. Foo … Read more
Ria Dancel Collaborates on Creation of Internal Medicine Residency POCUS Recommendations
Ria Dancel, MD Ria Dancel, MD, FACP, SFHM, FAAP, Professor of Medicine and Pediatrics in the UNC Division of Hospital Medicine, collaborated with a group of academic teaching physicians to develop the first expert and evidence-based consensus on the core components of a point-of-care ultrasound (POCUS) curriculum for internal medicine residency training in the United States. Thei … Read more
M. Bradley Drummond Found Promise in Using Digital Inhalers to Predict COPD Flare-ups
Dr.Brad Drummond M. Bradley Drummond, MD, MHS, a Professor of Medicine and the Director of the Obstructive Lung Diseases Clinical and Translational Research Center at UNC, published a pilot study in the Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation suggesting that digital inhaler technology may help predict worsening symptoms in COPD patients up to two we … Read more
Christopher Dittus Completes Meaningful Lymphoma Study He Started as a Fellow
Christopher Dittus, DO, MPH, Associate Professor of Medicine and Clinical Director of the lymphoma program, is the senior author of a newly published study in the British Journal of Haematology evaluating a novel treatment approach for aggressive adult T-cell leukemia/lymphoma (ATLL), a rare and deadly subtype of non-Hodgkin lymphoma that primarily affects ethnic minority populat … Read more
Richard Loeser Receives Department of Defense Grant for Investigating Post-Traumatic Oseteoarthritis
Richard Loeser, Jr., MD, Director of the Thurston Arthritis Research Clinic and a Joseph P. Archie Eminent Professor of Medicine, was awarded a $500K grant from the Department of Defense (DoD) for his study entitled,” A novel drug discovery approach for preventing post-traumatic osteoarthritis.” The DoD’s Arthritis Research Program Focused Research Award supports high-risk high-r … Read more
Fellow and Faculty Conduct Comparative C. Diff Study
Dr. Barlowe and Dr.McGill Sarah McGill, MD, MSc a gastroenterologist and endoscopist, and Trevor Barlowe, MD, a gastroenterology fellow, have found that a newly-approved treatment for C. diff. infection, called fecal microbiota spores, may be associated with a particularly harmful rebound of infection, compared to traditional therapy. Their results were published in Clinical Gast … Read more
Joshua Zeidner Co-Authored a Study on a Promising Novel Drug for Acute Myeloid Leukemia
Joshua Zeidner, MD Joshua Zeidner, MD, associate professor of medicine and chief of leukemia research at UNC Lineberger, is the corresponding author of a newly published study on a promising treatment approach for acute myeloid leukemia (AML). The early-phase clinical trial, conducted at 12 centers nationwide, tested whether adding the oral menin inhibitor revumenib to the standa … Read more
Drs. Jensen and Gray receive UNC SOM Physician Scientist Training Program Awards
Drs. Simon Gray (left) and Jeffrey Jensen (right) Jeffrey Jensen, MD, PhD, a hematology/oncology fellow, and Simon Gray, MD, PhD, an assistant professor in the Division of Gastroenterology and Hepatology, received UNC School of Medicine Physician Scientist Training Program awards. Dr. Gray received an Early-Stage Faculty award, and Dr. Jensen received a Resident/Fellowship Award, … Read more
John Buse Leads Study Finding Cushing’s Syndrome in a Quarter of Patients with Difficult-to-Control Diabetes
John Buse, MD, PhD, Verne S. Caviness Distinguished Professor of Medicine in the Division of Endocrinology & Metabolism, led a study finding 24% of individuals with difficult-to-control type 2 diabetes also present with hypercortisolism (Cushing’s syndrome). This study, entitled CATALYST and published in Diabetes Care, was the largest and most rigorous trial ever conducted to … Read more
Amanda Nelson Contributes to Landmark Osteoarthritis Study
Left to right: Amanda E. Nelson, MD, MSCR, RhMSUS; Liubov Arbeeva, MS; Yvonne Golightly, PT, MS, PhD Amanda E. Nelson, MD, MSCR, RhMSUS, professor of medicine in the Division of Rheumatology, Allergy and Immunology, and other Thurston Arthritis Research Center researchers coauthored a study entitled, “Translational genomics of osteoarthritis in 1,962,069 individuals” in Nature. T … Read more
Drs. Saira and Shehzad Sheikhs’ Project Voted First Place by Peers at FNIH Biomarkers Consortium
Saira Sheikh, MD, Linda Coley Sewell Distinguished Professor of Medicine in the UNC Division of Rheumatology, Allergy & Immunology and Director of the Clinical Trials Program at UNC’s Thurston Arthritis Research Center, along with her brother Shehzad Sheikh, MD, PhD, Professor of Medicine in the UNC Division of Gastroenterology & Hepatology, were invited to pitch their co … Read more