Category: Research News
Sheikh, Lee & Niethammer Receive $4.4 Million 2-Year NIH Award to Advance Multi-Modal Machine Learning for Earlier Diagnosis of Lupus
From left to right: Saira Sheikh, MD, Yueh Lee, MD, PhD, Marc Niethammer, PhD A rheumatologist, neuroradiologist, and computer scientist have joined forces to blend medical expertise with AI/machine learning to reimagine the future of lupus diagnosis and care. Saira Sheikh, MD, the Linda Coley Sewell Distinguished Professor of Medicine at UNC and Chair of the Lupus Clinical Inves … Read more
John Buse Co-Publishes ‘STEP UP T2D’ on the Efficacy of Higher Semaglutide Doses
John Buse, MD, the Verne S. Caviness Distinguished Professor of Medicine and Director of the UNC Diabetes Care Center, co-authored STEP UP T2D an international trial. STEP UP T2D found that a higher maintenance dose of semaglutide (7.2 mg once weekly) leads to significantly greater weight loss and improved blood sugar control in adults with type 2 diabetes and obesity, compared w … Read more
Center for Gastrointestinal Biology and Disease Receives 40th Consecutive Year of NIH Funding
Pictured are Dr. Robert Sandler and Julianne O’Daniel. Robert Sandler, MD, MPH, Professor of Medicine at the University of North Carolina at Chapel Hill and Director of the Center for Gastrointestinal Biology and Disease (CGIBD), has announced the renewal of the Center’s P30 Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This renew … Read more
Gaurav Dave to serve as Research Director for NIH’s Building Interdisciplinary Research Careers in Women’s Health Program
UNC-Chapel Hill has been announced as the recipient of a National Institutes of Health (NIH) Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) award. Created by the Office of Research on Women’s Health in partnership with NIH Institutes, Centers, and Offices, BIRCWH is a mentored career-development program designed to connect junior faculty to senior faculty … Read more
Shehzad Sheikh Identifies CADM1 as a Key Driver of Gut Inflammation in IBD Patients
Shehzad Z. Sheikh, MD, PhD A groundbreaking study co-led by Shehzad Z. Sheikh, MD, PhD, professor of medicine in the UNC Division of Gastroenterology and Hepatology, and Matthew N. Poy, PhD, associate professor of medicine with Johns Hopkins University, reveals Cell Adhesion Molecule 1 (CADM1), a surface protein involved in cell-cell adhesion, is significantly elevated in the int … Read more
PROMOTER Study Aims to Advance Translational Research in Esophageal Diseases
Researchers from the University of North Carolina and North Carolina State University aim to use a pig-based model to study esophageal diseases, a field where scientific understanding remains limited. Researchers use large animal models to help with therapy development, testing and translation. However, fully defined models of digestive diseases are still scarce. Within this fiel … Read more
UNC Joins Phase 3 CATT1 Trial Investigating Cadisegliatin as Adjunctive Therapy for Type 1 Diabetes
The University of North Carolina will serve as a study site for the vTv Therapeutics Inc. CATT1 Phase 3 trial investigating cadisegliatin as an adjunctive treatment to insulin in adults with type 1 diabetes (T1D). Cadisegliatin is a potential first-in-class, oral, liver-selective glucokinase activator for T1D that has been granted Breakthrough Therapy designation by the U.S. Foo … Read more
Ria Dancel Collaborates on Creation of Internal Medicine Residency POCUS Recommendations
Ria Dancel, MD Ria Dancel, MD, FACP, SFHM, FAAP, Professor of Medicine and Pediatrics in the UNC Division of Hospital Medicine, collaborated with a group of academic teaching physicians to develop the first expert and evidence-based consensus on the core components of a point-of-care ultrasound (POCUS) curriculum for internal medicine residency training in the United States. Thei … Read more
M. Bradley Drummond Found Promise in Using Digital Inhalers to Predict COPD Flare-ups
Dr.Brad Drummond M. Bradley Drummond, MD, MHS, a Professor of Medicine and the Director of the Obstructive Lung Diseases Clinical and Translational Research Center at UNC, published a pilot study in the Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation suggesting that digital inhaler technology may help predict worsening symptoms in COPD patients up to two we … Read more
Christopher Dittus Completes Meaningful Lymphoma Study He Started as a Fellow
Christopher Dittus, DO, MPH, Associate Professor of Medicine and Clinical Director of the lymphoma program, is the senior author of a newly published study in the British Journal of Haematology evaluating a novel treatment approach for aggressive adult T-cell leukemia/lymphoma (ATLL), a rare and deadly subtype of non-Hodgkin lymphoma that primarily affects ethnic minority populat … Read more
Richard Loeser Receives Department of Defense Grant for Investigating Post-Traumatic Oseteoarthritis
Richard Loeser, Jr., MD, Director of the Thurston Arthritis Research Clinic and a Joseph P. Archie Eminent Professor of Medicine, was awarded a $500K grant from the Department of Defense (DoD) for his study entitled,” A novel drug discovery approach for preventing post-traumatic osteoarthritis.” The DoD’s Arthritis Research Program Focused Research Award supports high-risk high-r … Read more
Fellow and Faculty Conduct Comparative C. Diff Study
Dr. Barlowe and Dr.McGill Sarah McGill, MD, MSc a gastroenterologist and endoscopist, and Trevor Barlowe, MD, a gastroenterology fellow, have found that a newly-approved treatment for C. diff. infection, called fecal microbiota spores, may be associated with a particularly harmful rebound of infection, compared to traditional therapy. Their results were published in Clinical Gast … Read more