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Category: Research News

  • MacNider Building

    Novel study finds aspirin-free regimen benefits patients with LVAD

    The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD). “There has been no consensus in the field about use of or dose of aspirin in the LVAD population until this stu … Read more

  • Amanda E. Nelson, MD, MSCR, RhMSUS

    Nelson Expresses Concern for Use of Methotrexate in Hand OA Following Clinical Trial

    “Many individuals with hand OA have multiple medical comorbidities and polypharmacy, which are important when considering additional treatments, particularly those with modest benefit and potential adverse effects over the long term,” she said.

  • October-Grants and Funding

    Department of Medicine Grants & Funding: October 1 – October 31, 2023

    Division of Infectious Diseases Edward P Browne, PhD, received a: R61 grant  from the NIDA to examine the impact of cannabinoids in HIV infected humanized mice. This is a five year, $3,465,157 grant. R21 grant from the NIAID to examine post therapy changes in CD4 T cells by single cell RNA sequencing. This award is $427,625. Nicholas Piazza, MD, received a $350,351 grant to intro … Read more

  • UNC Joins Osteoporosis Clinical Trial to Test Specialist-Fracture Liaison Service 

    Donald Caraccio, MD, principal investigator and assistant professor medicine, and Maya Styner, MD, associate professor of medicine, will lead a clinical site for the RESTORE study- REducing future fractureS and improving ouTcOmes of fRagility fracturE.    Bones in patients with osteoporosis often become fragile and have an increased risk for fracture or break. Known as fragility … Read more

  • Researchers create a community resource referral program to address kidney health disparities

    Drs. Gaurav Dave, associate professor of medicine, and Abhijit V. Kshirsagar, Covington Distinguished Professor of Medicine, received a grant from the NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to address structural racism to reduce kidney health disparities in rural North Carolina. North Carolina has the second largest rural population in the co … Read more

  • Ross Boyce, MD, MSc

    Dr. Boyce Receives $4.4 Million to Lead a Malaria Intervention Project in Uganda Following Extreme Weather Events

    The NIH has awarded a multi-disciplinary team led by Ross Boyce, MD, MSc, a $4.4 million, five-year (R01) grant to evaluate the effectiveness of a chemoprevention effort designed to prevent malaria outbreaks after flooding, using a combination of interventions. Boyce is a member of the Institute for Global Health and Infectious Diseases (IGHID), an Assistant Professor in the Divi … Read more

  • Five NC Institutions Collaborating to Advance Kidney, Urology, Hematology (KUH) Research

    Ronald Falk, MD, Nan and Hugh Cullman Eminent Professor of Medicine at UNC, Anthony Atala, MD, Professor of Medicine at Wake Forest University and Thomas Ortel, MD, PhD, Professor of Medicine at Duke University, will lead an effort to cultivate a highly skilled cohort of people and resources to advance research in kidney, urology, and hematology. Collaboration in medicine is comm … Read more

  • Gut Microbiome Can Increase Risk, Severity of HIV, EBV Disease

    Angela Wahl, PhD, Balfour Sartor MD, and J. Victor Garcia, PhD, and colleagues created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and Epstein-Barr virus. 

  • MacNider Building

    Study Shows Weight Loss Drug Reduces Cardiovascular Risk by 20% in Overweight, Obese Adults

    A new study shows semaglutide 2.4 mg (Wegovy), a weekly injected prescription medication for overweight adults, may prevent major adverse cardiovascular events (MACEs) such as cardiovascular death, non-fatal heart attack or non-fatal stroke. Novo Nordisk released the results of the significant clinical trial called SELECT. The trail studied the effects of Wegovy on people with ca … Read more

  • Evan S. Dellon, MD, MPH

    Dr. Dellon Ushers in First FDA-Approved Medication for Eosinophilic Esophagitis

    Evan Dellon, MD, MPH, a professor of medicine in the Division of Gastroenterology & Hepatology and director of the Center for Esophageal Diseases and Swallowing, co-leads effort to approve an allergy drug, dupilumab, for the treatment in adults and adolescents with eosinophilic esophagitis. Eosinophilic esophagitis (EoE) is an allergic condition of the esophagus that is on th … Read more

  • Lone star tick research

    Using Collaboration to Fight a Tricky Tick-Borne Disease

    Alpha-Gal Syndrome, or AGS, is a recently identified tick-borne disease that triggers an allergy to red meat and other products made from mammals, including cheese, gelatin, and medications like heparin. Since its discovery in 2009, cases in the United States alone have risen from 24 to >40,000 people, owing to the geographic spread of the tick populations and the fact that th … Read more

  • TARC Holds Fifth Annual “Research Day”

    Approximately 100 leading researchers and clinicians, research staff and trainees gathered recently to discuss innovative ways to advance research in arthritis, allergy, and autoimmune diseases. Additionally, attendees who couldn’t participate in person attended remotely. Of particular interest this year was keynote speaker and John B. Winfield, MD Visiting Scholar, Ali Ellebedy, … Read more