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The National Heart, Lung and Blood Institute renewed the Jensen Lab’s R01 funding for 5-years at $2.48 million for its project, “Metabolic mechanisms of cardioprotection through alpha-1A adrenergic receptor activation.” The grant will support ongoing investigation of the adaptive effects of alpha-1A adrenergic receptors on mitochondrial function in the heart. The proposed work also will seek to define whether antagonists of alpha-1A adrenergic receptors, commonly used to treat prostate disorders, adversely affect cardiometabolic risk.

The Jensen Lab is run by Brian Jensen, MD, associate professor of medicine and pharmacology. Co-investigators on the award are Kelsey Fisher-Wellman and Jessica Ellis from East Carolina University.

Read more about the Jensen Lab.