Research News
Dr. Dellon Ushers in First FDA-Approved Medication for Eosinophilic EsophagitisEvan Dellon, MD, MPH, a professor of medicine in the Division of Gastroenterology & Hepatology and director of the Center for Esophageal Diseases and Swallowing, co-leads effort to approve an allergy drug, dupilumab, for the treatment in adults and adolescents with eosinophilic esophagitis. Eosinophilic esophagitis (EoE) is an allergic condition of the esophagus that is … Continued
Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogensMalaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination treatment sulfadoxine-pyrimethamine (SP), given for intermittent preventive therapy of malaria in pregnancy (IPTp), is one of the few existing interventions that improve outcomes for both mother and baby, despite widespread SP-resistant malaria. Compelling evidence has shown malaria-independent … Continued
Department of Medicine Faculty Featured in School of Medicine 2021 Annual Research ReportAs we all desperately await a way to treat COVID-19, beyond prevention, the following publication has metrics that are incredible (following February publication, by December 2021 it had been accessed >107K times with a >1700 Altimetric).
Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTEKlara R. Klein, MD, PhD, fellow in the division of endocrinology and metabolism and trainee in the UNC Physician Scientist Training Program, and John Buse, MD, PhD, chief of the division of endocrinology and metabolism, are authors of a new study published in BMJ Open Diabetes Research and Care. Hemoglobin glycation index is the difference between … Continued
Ribiero Publishes “Impact of Airway Inflammation on the Efficacy of CFTR Modulators” in the Journal CellsCarla Ribiero, PhD, professor of medicine in the division pulmonary and critical care medicine, expands the understanding of how airway inflammation improves CFTR rescue and may benefit cystic fibrosis patients, in a new review published in Cells. The cystic fibrosis transmembrane conductance regulator (CFTR) protein is responsible for regulating the proper flow of chloride and … Continued
Carey Discussed Studies of HR-Positive and HER2-Negative Advanced Breast Cancer: Overall Survival by Subtype Across Three MONALEESA StudiesLisa A. Carey, MD, FASCO, the L. Richardson and Marilyn Jacobs Preyer Distinguished Professor for Breast Cancer Research, Division of Oncology and Deputy Director of Clinical Sciences for the Lineberger Comprehensive Cancer Center, discusses findings from a pooled analysis of the MONALEESA-2, -3, and -7 trials. Among the findings was a consistent overall survival benefit with … Continued
Peery Lead Author of Study on Burden and Cost of GI, Liver and Pancreatic DiseasesAnne Peery, MD, MSCR, associate professor in the Division of Gastroenterology and Hepatology, is the corresponding author of a new article, “Burden and Cost of Gastrointestinal, Liver and Pancreatic Diseases in the United States: Update 2021,” published October 19 in Gastroenterology. The study concluded, “Gastrointestinal diseases are responsible for millions of health care encounters and … Continued
Phase 3 Data Show Monoclonal Antibodies Provide long-term Protection Against COVID-19A single dose of REGEN-COV, a combination monoclonal antibody therapy, reduced the risk of COVID-19 by 81.6% several months after a single dose. UNC School of Medicine’s Myron Cohen, MD, leads monoclonal antibody research efforts as part of the NIH-sponsored COVID Prevention Network. Regeneron Pharmaceuticals, Inc. announced additional positive results from a phase 3 clinial … Continued
Batsis receives NC TraCS Institute grant to explore the early detection of sarcopeniaThe NC TraCS Institute has awarded John A. Batsis, MD, and the Division of Geriatric Medicine a 1-year, team science grant to study the early detection of sarcopenia.
Muss Receives Three Research Grant AwardsHyman Muss, MD, the Mary Jones Hudson Distinguished Professor of Geriatric Oncology in the Division of Oncology, recently received three research awards. From the Breast Cancer Research Foundation (BCRF), Muss received $190,000 in funding for “p16INK4a Expression, Chemotherapy Toxicity, and Aging in Women with Breast Cancer.” There is significant variability in chemotherapy-related toxicity in women of … Continued