SLEEP
A Randomized Trial of CPAP for Sleep Apnea in
Pregnancy (SLEEP)
The goal of this study is to understand if using CPAP in pregnancy can help women have healthier pregnancies.
Sleep Apnea and CPAP Machines:
- Sleep Apnea is a sleep disorder in which breathing repeatedly stops and starts during sleep
- Symptoms may include loud snoring and waking up repeatedly at night
- Continuous Positive Airway Pressure (CPAP) is the most commonly prescribed treatment for sleep apnea
- CPAP provides air at a higher pressure to prevent airway collapse and allow for better sleep
You may be right for this study if:
- You are 14 to 21 weeks pregnant with one baby
This study is not right for you if:
- You are already receiving treatment for sleep apnea
- You take sleeping pills for insomnia
- You are pregnant with twins
If you are not sure if you qualify please contact us so we can help guide you.
*This study will be recruiting through spring of 2026 and participants will be compensated for their time*
More Information
This study is funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH). Conducted by the NICHD Maternal-Fetal Medicine Units (MFMU). All biostatistical information is the responsibility of the Data Coordinating Center (DCC) at George Washington University.
IRB#: 18-0647
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Facco FL, Kramer J, Ho KH, Zee PC, Grobman WA. Sleep disturbances in pregnancy. Obstet Gynecol. Jan 2010;115(1):77-83.
Chen YH, Kang JH, Lin CC, Wang IT, Keller JJ, Lin HC. Obstructive sleep apnea and the risk of adverse pregnancy outcomes. American journal of obstetrics and gynecology. Sep 16 2011.
Facco FL, Parker CB, Reddy UM, et al. Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus. Obstet Gynecol. Jan 2017;129(1):31-41.
McMillan A, Bratton DJ, Faria R, et al. Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial. The Lancet. Respiratory medicine. Oct 2014;2(10):804-812.
Martinez-Garcia MA, Campos-Rodriguez F, Catalan-Serra P, et al. Cardiovascular mortality in obstructive sleep apnea in the elderly: role of long-term continuous positive airway pressure treatment: a prospective observational study. American journal of respiratory and critical care medicine. Nov 01 2012;186(9):909-916.
