Graham Diering, PhD, Interviewed on Radio in Vivo
June 4, 2018
Graham Diering, PhD, was interviewed on Radio in Vivo, a local Triangle weekly science interview radio program, about the science of sleep.
Category: News
Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells
April 23, 2018
The Dokholyan and Deshmukh labs published a report in PNAS where they examined the neurotoxicity of various SOD1 protein aggregates in a model of Amyotrophic Lateral Sclerosis (ALS). The large SOD1 aggregates, which are a hallmark of ALS, are generally considered to contribute to motor neuron death in ALS. However, the study found that the large SOD1 aggregates are less toxic than the smaller SOD1 trimers. These results suggest that therapies targeted towards the SOD1 trimers, rather than the larger SOD1 fibrils, may be more effective for the treatment of ALS.
Nagendran Muthusamy, PhD, Wins 2018 Robert & Margaret Grossfeld Award
April 16, 2018
Matsushima Lab Research Scientist, Nagendran Muthusamy, is the 2018 Robert and Margaret Grossfeld Award Recipient. This award recognizes his outstanding 2017 publication in Nature Neuroscience.
Bryan Roth, MD, PhD, to give Presidential Special Lecture at 2018 SFN Meeting
April 16, 2018
UNC investigator, Bryan Roth, will give a Presidential Special Lecture entitled “From Salvia Divinorum to LSD—Toward a Molecular Understanding of Psychoactive Drug Actions” at the 2018 meeting of the Society for Neuroscience.
Graham Diering, PhD, Publishes in PNAS
April 3, 2018
Memories can last a lifetime, but the neuronal synapses that store memories are made of macrolmolecules such as proteins that undergo synthesis and degradation on the scale of hour to days. The Huganir Lab, in which Dieiring was recently a postdoctoral scholar, hypothesized that a population of extremely long-lived proteins may reside at synapses, forming part of the substrate for long-term storage of memories. Here they have used metabolic labeling of mice and cultured neurons, combined with mass spectrometry to identify the synaptic long-lived proteome.
Song Lab Publishes Cover Article of Stem Cell Reports
March 13, 2018
The latest publication from the Song Lab, “An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus”, has made the cover of Stem Cell Reports!
UNC to Host Brain Stimulation Conference
March 5, 2018
Spearheaded by Flavio Frohlich, PhD, the conference will gather the top minds in the field of neurostimulation this May in Chapel Hill. Registration is now open.
Freiwald, Tsao win 18th Perl-UNC Neuroscience Prize
January 30, 2018
The UNC School of Medicine has awarded the 18th Perl-UNC Neuroscience Prize to Winrich Freiwald, PhD, of The Rockefeller University and Doris Y. Tsao, PhD, of the California Institute of Technology for the discovery of brain mechanisms of face recognition.
Freiwald and Tsao will visit Chapel Hill on April 12 to receive the prize – a $20,000 award – and give a lecture on their work at 3 p.m. in room G202 in the Medical Biomolecular Research Building (MBRB).
Hyejung Won & Jason Stein Publish in Cell
January 16, 2018
Jason Stein and Hyejung Won recently published an article in Cell on the dynamic landscape of open chromatin during human neurogenesis.
UNC Scientists Take a Big Step toward Building a Better Opioid
January 12, 2018
In a paper published in Cell, UNC School of Medicine researchers led by Bryan Roth, MD, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.