Gary L. Johnson |
| Clinical / Research Focus: Spatio-temporal regulation of signal relay systems in cells using live cell fluorescence imaging and targeted gene disruption of signaling proteins to define their role in development, physiology and … Read more |
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AFFILIATIONS: Lineberger Cancer Center, Pharmacology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Biophysics, Cancer Biology, Structural Biology |
Hengming Ke |
| Clinical / Research Focus: Our research focuses on the structure and function of medically important proteins from the crystallographic approach. The current topics include cycolphilin, calcineurin, heat shock protein 90 (hsp9 … Read more |
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AFFILIATIONS: Biochemistry & Biophysics |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Molecular Medicine, Structural Biology, Translational Medicine |
Sergey Krupenko, PhD |
| Clinical / Research Focus: Dr. Krupenko’s research is focused on the role of folate metabolism in cellular homeostasis and cancer disease. He is especially interested in the function of a major folate enzyme and a putative tumo … Read more |
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AFFILIATIONS: Nutrition |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Cancer Biology, Cell Signaling, Metabolism, Structural Biology |
Brian Kuhlman |
| Clinical / Research Focus: We use a combination of experimental and computational methods to redesign protein-protein interactions. The potential applications for this technology include enhancing protein therapeutic and creat … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology |
CLINICAL/RESEARCH INTERESTS: Biophysics, Chemical Biology, Computational Biology, Structural Biology |
Prem Lakshmanane, PhD |
| Clinical / Research Focus: Research in my laboratory has three interlinked focus areas: 1. IMMUNE RESPONSE TO INFECTION AND VACCINATION: Cutting-edge approaches to evaluate coronavirus and arbovirus antibody responses in … Read more |
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AFFILIATIONS: Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Immunology, Molecular Biology, Structural Biology, Virology |
Andrew L. Lee, PhD |
| Clinical / Research Focus: We study protein structure and dynamics as they relate to protein function and energetics. We are currently using NMR spectroscopy (e.g. spin relaxation), computation, and a variety of other biophysic … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Pharmaceutical Sciences |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Computational Biology, Structural Biology |
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AFFILIATIONS: Pharmaceutical Sciences |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Chemical Biology, Molecular Biology, Structural Biology |
Matthew Ryen Lockett, PhD |
| Clinical / Research Focus: Research in the Lockett group focuses on the development of analytical model systems to: i) chemically modify the surface of thin films, and study chemical and biochemical reactions occurring on those … Read more |
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AFFILIATIONS: Chemistry |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Structural Biology |
Gregory Matera, PhD |
| Clinical / Research Focus: The research in our laboratory focuses on foundational mechanisms that regulate eukaryotic gene expression. In particular, we are interested in the roles played by RNAs and proteins in genetic … Read more |
| Mentors: | Undergraduate Students, Graduate Students |
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AFFILIATIONS: Biochemistry & Biophysics, Pharmaceutical Sciences |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Chemical Biology, Molecular Biology, Structural Biology |
Saskia Neher |
| Clinical / Research Focus: Our lab seeks to better understand the maturation and regulation of a group of human lipases. We aim to uncover how these lipases properly fold and exit the ER, and how their activity is subsequently … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, McAllister Heart Institute |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Cardiovascular Biology, Molecular Biology, Structural Biology |



