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I study how the intestinal epithelium regulates stem cell activity with a focus on cell cycle and metabolic regulation. Models include primary human and mouse 2D monolayers and 3D organoids in vitro and mouse in vivo genetic models. I also have extensive experience in stem cells and injury response in the muringe gastric epithelium.
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UNC AFFILIATIONS:
Biomedical Engineering, Center for GI Biology and Disease (CGIBD) |
CLINICAL/RESEARCH INTERESTS:
Cell Biology, Cell Signaling, Gastrointestinal Biology, Genetics, Metabolism, Microscopy, Stem Cells |