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PERSONAL WEBSITE:
https://www.med.unc.edu/pathology/directory/melinda-yates-phd/ |
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My research program is focused on cancers that form in the lining of the uterus (endometrium) with a particular emphasis on premalignant biology. My lab studies the earliest molecular changes that occur in the endometrium during cancer development related to obesity and hereditary DNA mismatch repair defects (Lynch syndrome).
By first defining mechanisms related to environmental factors (obesity, hormones, and exposures linked with social determinants of health) that influence endometrial cancer development and disparities, we ultimately aim to use pharmacologic agents to prevent, block, or reverse endometrial cancer development and improve outcomes for women.
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UNC AFFILIATIONS:
Lineberger Cancer Center, Pathology & Lab Medicine, Translational Medicine, Women's Health |
CLINICAL/RESEARCH INTERESTS:
Cancer, Cancer Biology, Drug Delivery, Health Equity, Obesity, Other, Pathology, Pharmacology, Social Determinants of Health, Toxicology, Translational Medicine, Women's Health |