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Our work focuses on T cell-mediated autoimmunity with a particular interest in type 1 diabetes. Efforts involve defining the events driving the breakdown of self-tolerance within the T cell compartment as well as developing immunotherapies that selectively target the autoimmune response and reestablish long-term self-tolerance.


UNC AFFILIATIONS:

Lineberger Cancer Center, Microbiology & Immunology

CLINICAL/RESEARCH INTERESTS:

Cell Signaling, Diabetes, Gene Therapy, Immunology, Molecular Medicine, Nanomedicine, Pathology, Translational Medicine