Organization: UNC / UNC Health

The primary mission of my laboratory is to elucidate the mechanisms that underlie pain perception and its modulation by opioids. We investigate the sensory, affective, and cognitive dimensions of pain experience, and both the analgesic and side effects of opioids, including addiction and respiratory depression. Our experimental strategies use a...

Breast cancer Health services research Quality of care Patient safety Performance improvement

Dr. Kreda’s lab studies mechanisms of delivery of therapeutic molecules in the lung and other extra-hepatic organs. The main goal is to develop novel and efficacious delivery strategies of therapeutic nucleic acids in obstructive lung diseases. The Kreda lab is currently involved in designing an efficacious oligonucleotide-based therapeutic approach to...

I am a licensed speech-language pathologist at the Carolina Institute for Developmental Disabilities (CIDD) and clinical instructor in the Department of Psychiatry at the UNC-CH. Since 2005, I have been involved in research focusing on individuals with a range of developmental disabilities, such as autism spectrum disorders, fragile X syndrome,...

Matthew Painschab, MD, bridges two worlds as a clinician and researcher, treating patients with hematologic malignancies in Chapel Hill and at our partner site in Malawi, UNC Project Malawi. His primary research interest is in HIV-associated cancers, especially virally mediated cancers including multicentric Castleman disease, lymphoma and Kaposi sarcoma. Dr....

I am medical director of the inpatient crisis stabilization unit and of the resident psychotherapy clinic. Areas of clinical focus include suicide, mood disorders, substance use, and psychotherapy.

Mental disease, including addiction and neurodegeneration, are central themes of Dr. Crews’s research. Addiction has many components, one of which is long-term changes in gene expression and structure in brain. Binge drinking-induced changes in specific brain regions is hypothesized to contribute to the progression to addiction. This could overlap with...

Other Research and/or Clinical Interests: – Echocardiography – Valvular Heart disease – Critical Care – Inpatient QI initiatives

My research program lies at the intersection of autism services, mental health, and implementation science. My work focuses on improving community services for people on the autism spectrum across the lifespan. I am particularly interested in engaging autistic individuals and other stakeholders in community-partnered research, preventing suicide and self-harm in...

I have extensive training in movement disorders under the tutelage of Dr. Stanley Fahn. For the past fifteen years I am seeing exclusively movement disorder patients at the Neurology Department of University of North Carolina (UNC). Since becoming Director of the Movement Disorders Clinic at UNC (MDC UNC), my colleagues...

Our interest is in the cellular interactions, protein chemistry, and enzyme kinetics that are behind the molecular mechanisms of both healthy hemostasis and the dysregulation of hemostasis seen in bleeding and thrombosis. Part of our research focus is the mechanisms of novel coagulation molecules and novel antithrombotics. A main focus...

Dr. Jewell currently leads a large interprofessional type 1 diabetes research and wellness lab that focuses on community-engaged research. She engages in research aimed to improve diabetes-related health outcomes, access to rural healthcare, and engagement of stakeholders in the research process, specifically for families with a young child living with...