Organization: UNC / UNC Health

I am trained in neuroscience with specialty in viral and non-viral nano-biomaterials-mediated gene/drug therapy. My research focuses on the use of nanotechnologies and biocompatible materials to develop safe and effective gene and drug therapies for limiting the effects of retinal blinding diseases. My focus for over fifteen years has been...

Dr. Ehre’s laboratory specializes in the biochemical and biophysical properties of mucus, which are affected in various airway diseases such as asthma, cystic fibrosis (CF), and chronic obstructive pulmonary disease (COPD). Studies conducted in her laboratory utilize cell cultures, small animal models, and human specimen to gain insights into pathogenesis...

Other Research and/or Clinical Interests: cancer risk, cancer screening, quantitative imaging, cancer epidemiology

Dr. Rose’s clinical interest is in the treatment of patients with genitourinary cancers, including bladder, kidney, prostate, and testicular cancers. She has a focus on the development of novel therapies and combination therapies for patients with urologic malignancies, including the design and implementation of clinical trials. She also studies the...

The Merker Laboratory is focused on translating novel molecular biomarkers into clinical oncology practice. The overarching goal of this work is to improve the care and survival of patients with cancer. The biomarker development life cycle is a challenging multistep process, and our group works on projects at each step,...

Our lab is interested in epigenetic and transcriptional regulation of conventional and unconventional T cell development, differentiation and function. Our research aims to decipher how aberrations in T cell biology can result in disease emergence such as inflammation, autoimmunity and cancer. We also aim to understand how we can reprogram...

My research focuses on family planning (HIV and contraception, postpartum family planning), cervical cancer screening and preventive therapy, and maternal health inequities.

The Pattenden lab is focused on the development of innovative techniques in chromatin-based therapeutic target discovery and cancer diagnostics. As Director of Applied Epigenetic Screening Technologies at the Center for Integrative Chemical Biology and Drug Discovery, my goal is to enable collaborators to apply chemical biology to the discovery of...

My lab examines how inhaled agents modify respiratory immune responses using a number of translational research models. My group is particularly interested in how inhaled agents, such as ambient air pollutants, ozone, woodsmoke, cigarette smoke, and aerosols, such as e-cigarettes, modify respiratory immune health and exacerbation of pre-existing diseases, such...

My research focuses on the transmission and prevention of transmission of microbial pathogens. I helped to develop laboratory methods to measure HIV in genital secretions, as well as methods to determine the best antiviral agents to reduce replication of HIV in these compartments. I was Principal Investigator of the multinational...

The overall focus of research in my laboratory is to improve the diagnosis and treatment of airway diseases, especially those that result from impaired mucociliary clearance. In particular, our efforts focus on the diseases cystic fibrosis and primary ciliary dyskinesia, two diseases caused by genetic mutations that impair mucociliary clearance...