Organization: UNC / UNC Health

The ultimate goal of our research is to understand how adaptive changes in brain function occur and how this can lead to the development of psychiatric disorders. We employ cutting-edge technologies to understand the complex interactions of multiple neural systems that allow us to adapt to our environment and regulate...

Other Research and/or Clinical Interests: Hernia, Abdominal Wall Reconstruction, Mesh, Simulation, Surgical Education, Video Coaching, Ergonomics

We study the molecular mechanisms of signal transduction by two-component regulatory systems, which involve sensor kinases, histidine phosphotransferases, and response regulators. We primarily focus on phosphorylation and dephosphorylation reactions using purified proteins and a variety of biochemical and biophysical methods. We explore both qualitative (what reactions occur) and quantitative (measure...

The Ideraabdullah lab uses a combination of molecular biology and omics approaches to study how gene-environment interactions in the fetal/developmental environment modulate the epigenome to program the trajectory of health & disease. We focus on reproductive health and liver metabolic health outcomes and use a combination of mouse models and...

Broadly speaking, my research interests lay in the arena of gene-environment interactions (GxE) in obstructive respiratory diseases. I view the identification and characterization of GxE as a means by which to understand population and individual-level disease susceptibility and a way to identify new disease mechanisms. My lab’s research has addressed...

Flavivirus pathogenesis -Immune mechanisms that control Zika virus and other congenital infections -Zika virus infection in the female reproductive tract -Host genetic determinants of neuroinvasive flavivirus pathogenesis -Viral and host mechanisms that control flavivirus infection in the skin -Viral determinants of Zika virus replication and pathogenesis -No-known-vector flaviviruses IFN-λ mediated...

Human-to-mosquito transmission of malaria: Efforts to eliminate malaria altogether hinge on the ability to prevent transmission. We showed that single dose primaquine added to ACT is effective in blocking transmission of multidrug resistant parasites to mosquitoes. We have used mosquito feeding studies to demonstrate the importance of microscopic gametocytemia as...

I am practicing pulmonologist specializing in COPD, as well as a clinical and translational researcher whose research focus includes characterizing the mechanisms for development of chronic lung disease in individuals at-risk or with chronic obstructive pulmonary disease (COPD). I have expertise in epidemiology and clinical trials design, and have applied...

My clinical interest is coagulation, with a particular focus on thrombosis and anticoagulation. My research interests include clinical trials on new anticoagulants and better use of established anticoagulants. I takes a special interest in clinical-medical education of healthcare professionals, patients and the public, and am a cofounder of the UNC...

I am an innate immunologist with a focus on pulmonary infections including viral (influenza, SARS-CoV-2) and bacterial (Streptococcus pneumoniae). My training background is in signaling biochemistry and cell biology and the lab focuses on pathways like TBK1/IRF and mTOR in macrophages and neutrophils. We use a combination of mouse models...

I am an Associate Professor of Pediatrics and Neurology at the University of North Carolina with a joint appointment in the Department of Neurology appointment and the Carolina Institute for Developmental Disabilities (CIDD). I am Co-Founder and Co-Director of the CIDD Clinical Trials Program. My clinical and research focus is...