Organization: UNC / UNC Health

Research in my laboratory focuses on the effects of air pollution and other environmental pollutants on the cardiovascular and respiratory systems. We use both traditional as well as novel physiological approaches (radiotelemetry, HF echocardiography, physiological challenge testing) to determine not only the short-term effects of exposure, but also the long-term...

Research in my laboratory focuses on how animals produce and control movement, with a particular interest in animal flight.  We use both computational and experimental techniques to examine how organismal components such as the neuromuscular and neurosensory systems interact with the external environment via mechanics and aerodynamics to produce movement...

We study alphavirus infection to model virus-induced disease.  Projects include 1) mapping viral determinants involved in encephalitis, and 2) using a mouse model of virus-induced arthritis to identify viral and host factors associated with disease.,We study alphavirus infection to model virus-induced disease.  Projects include 1) mapping viral determinants involved in...

Our preclinical research is based on the concept that drugs of abuse gain control over behavior by hijacking molecular mechanisms of neuroplasticity within brain reward circuits. To understand this process, we take a multidisciplinary preclinical approach that combines state-of-the-art behavioral methods with a variety of molecular, genetic, and pharmacological approaches....

Research in my laboratory investigates human cognition. We use behavioral measures and scalp-recorded event-related brain potentials (ERPs) to gain a better understanding of the rapid neural dynamics underlying cognitive processes, such as the interactions between attentional capture, sustained attention, and distraction.  We also use fMRI to investigate the neural architecture...

bioinformatics, scholarly communications, digital libraries, user interface design, annotation, virtual environments, medical informatics, databases and datamining.,bioinformatics, scholarly communications, digital libraries, user interface design, annotation, virtual environments, medical informatics, databases and datamining.

My research interests and diagnostic responsibilities center around nephropathology and immunopathology. My laboratory carries out basic, translational and clinicopathologic research on kidney diseases. I am most interested in pathogenic mechanisms and pathologic manifestations of glomerular diseases and vasculitis. A major current research focus is on elucidating the pathogenesis of vascular...

Spatio-temporal regulation of signal relay systems in cells using live cell fluorescence imaging and targeted gene disruption of signaling proteins to define their role in development, physiology and pathophysiology.,Spatio-temporal regulation of signal relay systems in cells using live cell fluorescence imaging and targeted gene disruption of signaling proteins to define...

The goal of my research is to identify, clone, and characterize the evolution of genes underlying natural adaptations in order to determine the types of genes involved, how many and what types of genetic changes occurred, and the evolutionary history of these changes. Specific areas of research include: 1) Genetic...