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Hippocampal Threat Reactivity Interacts with Physiological Arousal to Predict PTSD Symptomology

August 1, 2022
This study tested how threat-processing in hippocampus, a brain structure critical for forming memories of situations that are dangerous and safe, relates to development of post-traumatic stress disorder (PTSD). Using brain-imaging techniques coupled with laboratory and survey-based tests for trauma, the researchers found that individuals who showed less activity in...

The Toll-like receptor 7 agonist imiquimod increases ethanol self-administration and induces expression of Toll-like receptor related genes

August 1, 2022
This paper shows that activation of neuroimmune signaling can promote increases in alcohol drinking.

Biological constraints on stereotaxic targeting of functionally-defined cortical areas

August 1, 2022
This study finds marked inter-individual variability in the locations of functional cortical areas, making standardized atlas-based targeting unreliable. This report urges the field to adopt functional mapping in individuals before targeting, which should help researchers obtain reproducible data without erroneously pooling multiple functional areas.

Adolescent, parent, and provider perspectives on school-related influences of mental health in adolescents with suicide-related thoughts and behaviors

August 1, 2022
We explored how adolescents, their parents, school professionals, and hospital professionals viewed school as it positively or negatively influences adolescent mental health. Findings underscore the need for school-based approaches to address the unique academic, social, and emotional needs of students with suicide-related risk that complement the supports and services provided...

Effects of gonadal steroids on reward circuitry function and anhedonia in women with a history of postpartum depression.

August 1, 2022
We showed that the pregnancy hormones estrogen and progesterone can be used to turn on and turn off symptoms of depression in women. We also showed that these hormones reduce activity in areas of the brain that respond to rewards, which may help explain why some women do not experience...

Congratulations Karen Bluth, PhD on your book, “The Self-Compassionate Teen” a making it to Choose Therapy’s Best Anxiety Books of 2022!

July 29, 2022

A new study shows how decreased hippocampus engagement is associated with the development of posttraumatic stress disorder. Sam McLean, MD, MPH, leads the NIH-funded AURORA study.

July 28, 2022

Welcome Julia Riddle, MD to our Center for Women’s Mood Disorders!

July 28, 2022

Pregnant Patients With Panic Attacks Deserve Treatment. Yes, Sometimes Even With Medication!

July 28, 2022

Welcome to the faculty Dr. Michael Kane!

July 25, 2022