Institution:
University of North Carolina School of Medicine
About:
Identification of airway epithelial stem cells; innate immunity in the airway; the pathophysiology of post-lung transplant ischemia reperfusion injury and bronchiolitis obliterans syndrome.
My laboratory research is focused on basic cell biology questions as they apply to clinical lung disease problems. Our main work recently has been contributing to the NIH NHLBI Lung Repair and Regeneration Consortium, in which we are examining factors regulating airway and distal lung epithelial growth and differentiation, with a focus on regulation of stemness and differentiation of the key epithelial cell types. I contribute to UNC team science efforts on cystic fibrosis and aerodigestive cancers and direct a highly respected tissue procurement and cell culture Core providing primary human lung cells and other resources locally, nationally and internationally. I am the inaugural co-director of the Respiratory Block and am the “Physiology Coil” in the new UNC Translational Educational Curriculum for medical students and also teach in several graduate level courses.
