Data

GWAS Summary Statistics for Brain Imaging Phenotypes

Involved datasets: UK Biobank (UKB), Adolescent Brain Cognitive Development (ABCD) Study, Human Connectome Project (HCP), Philadelphia Neurodevelopmental Cohort (PNC), Alzheimer’s Disease` Neuroimaging Initiative (ADNI), Pediatric Imaging, Neurocognition, and Genetics (PING)

Terms of Use:

• By downloading these data, you acknowledge that they will be used for research purposes and that you are in compliance with applicable rules, policies and regulations.
• When reporting results of research that utilizes these data we request that you cite the original publication.

GWAS summary statistics for 382 Shape imaging traits

• Sample size: n=32631
• Version: Sep 18, 2022
• Download Summary Statistics:
  All data available for download at LINK
• Citation: Zhao et al (2022) Genetic influences on the shape of brain ventricular and subcortical structures. Preprint available at https://www.medrxiv.org/content/10.1101/2022.09.26.22279691v1

GWAS summary statistics for 82 Heart imaging (cardiac MRI) traits

• Sample size: n=31875
• Version: Oct 20, 2022
• Download Summary Statistics:
  All data available for download at LINK
• Citation: Zhao et al (2021) Heart-brain connections: phenotypic and genetic insights from 40,000 cardiac and brain magnetic resonance images. Preprint available at https://www.medrxiv.org/content/10.1101/2021.11.01.21265779v1

GWAS summary statistics for 200 resting-state functional MRI (rs-fMRI) traits

• Sample size: n=34,691
• Version: July 15, 2020
• Download Summary Statistics:

  wget --no-check-certificate --content-disposition https://raw.githubusercontent.com/stat-yyang/sumstats/master/fMRI.list
  wget -i fMRI.list

• Description: readme
• Citation: Zhao et al (2020) Common variants contribute to intrinsic functional architecture of human brain. Preprint available at https://doi.org/10.1101/2020.07.30.229914.

GWAS summary statistics for 215 tract-specific diffusion tensor imaging (DTI) parameters

• Sample size: n=33,292
• Version: July 15, 2020
• Download Summary Statistics:

  wget --no-check-certificate --content-disposition https://raw.githubusercontent.com/stat-yyang/sumstats/master/DTI.list
  wget -i DTI.list

• Description:  readme
• Citation: Zhao et al. (2020) Common genetic variation influencing human white matter microstructure. Preprint available at https://doi.org/10.1101/2020.05.23.112409.

GWAS Summary Statistics for 101 Brain Regional Volumes

• Sample size: n=19,629
• Version: May 24, 2019
• Download links:     GWAS Summary Statistics       readme (UK Biobank)       readme (meta-analysis)
• Citation: Zhao et al. (2019) Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health` Traits. Nature Genetics. https://www.nature.com/articles/s41588-019-0516-6

GWAS summary statistics for 110 brain regional diffusion tensor imaging (DTI) parameters

• Sample size: n=17,706
• Version: March 11, 2019
• Download links:     GWAS Summary Statistics       readme
• Citation: Zhao et al. (2019) Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health` traits (n=17,706). Molecular Psychiatry. https://www.nature.com/articles/s41380-019-0569-z