FALL COURSES

Course Syllabus (Click to download)

EXPERIMENTAL PHYSIOLOGY OF HUMAN HEALTH & DISEASE (CBPH 852 Fall) (4.5 credits). Students will learn the principles of cell, organ and systems physiology and pathophysiology required to identify and understand important areas of current biomedical research. Companion course to CBPH 853. Both courses emphasize different physiological systems: 852 covers the cardiovascular, respiratory, and endocrine systems, while 853 covers the digestive, renal and neurologic systems. Lectures emphasize examples of specific diseases (channelopathies, schizophrenia, hypertension, diabetes, etc) and current research opportunities. CBPH 853 also includes background on the ethical use of human subjects, and discusses approaches that utilize human samples or human genomics, while CBPH 852 provides background on non-human model systems (cultured cells, mice, zebrafish, drosophila, etc). In addition to lectures and ample time for in-class discussions, both courses will have a strong emphasis on the current research literature and will include journal-club discussion of assigned papers. For assistance with enrolling, please contact Janice Warfford, janice_warfford@med.unc.edu. If any additional course questions, please contact , Course Director, Scott Parnell, scott_parnell@med.unc.edu. MWF 9:00-10:30AM, 5201 MBRB, Lecture Course/Paper Discussions

Course Syllabus (Click to download)

Spring Courses

MODERN CONCEPTS IN CELL BIOLOGY II (CBPH 851/Spring) (4 credits). Literature based discussion course on experimental approaches in Cell Biology. Emphasis is on small group discussion and dissection of primary literature including methods, scientific logic, and critical thinking. Each session typically includes both a discussion of key background by a faculty member and student led discussions of selected papers from the primary literature. The course includes blocks on Cell Signaling, Cell Differentiation, Cell Cycle/Cell Death, Cytoskeleton/Motility, and Adhesion. For assistance with enrolling, please contact Janice Warfford, janice_warfford@med.unc.edu. If any additional course questions, please contact , Course Director, Richard Cheney, richard_cheney@med.unc.edu. T Th 3:00-5:00 pm. 6201 MBRB Paper Discussions.

Course Syllabus (Click to download)

EXPERIMENTAL PHYSIOLOGY OF HUMAN HEALTH & DISEASE (CBPH 853/Spring) (4.5 credits). Students will learn the principles of cell, organ and systems physiology and pathophysiology required to identify and understand important areas of current biomedical research. Companion course to CBPH 852. Both courses emphasize different  physiological systems: 852 covers the cardiovascular, respiratory, and endocrine systems, while 853 covers the digestive, renal and neurologic systems. Lectures emphasize examples of specific diseases (channelopathies, schizophrenia, hypertension, diabetes, etc) and current research opportunities. CBPH 853 also includes background on the ethical use of human subjects, and discusses approaches that utilize human samples or human genomics , while CBPH 852 provides background on non-human model systems (cultured cells, mice, zebrafish, drosophila, etc). In addition to lectures and ample time for in-class discussions, both courses will have a strong emphasis on the current research literature and will include journal-club discussion of assigned papers. For assistance with enrolling, please contact Janice Warfford, janice_warfford@med.unc.edu. For assistance with enrolling, please contact Janice Warfford, janice_warfford@med.unc.edu. If any additional course questions, please contact , Course Director, Carol Otey, carol_otey@med.unc.edu. MWF 9:00-10:30AM, 5201 MBRB, Lecture Course/Paper Discussions

Course Syllabus (Click to download)

ADVANCED LIGHT MICROSCOPY (CBPH 710/ Spring). The purpose of this course is to become “hands on” proficient in cutting edge microscope techniques and gain comfort using advanced microscopes available to researchers at UNC. This course will focus on advanced quantitative fluorescence microscopy techniques used for imaging a range of biological specimens, from whole organisms, to tissues, to cells, and to single molecules. This course emphasizes the quantitative issues that are critical to the proper interpretation of images obtained with light microscopes. The course will cover the Fundamentals of optics and fluorescent probes and dyes; Confocal and Widefield microscopy methods; Live cell microscopy considerations; Advanced microscopy techniques, and an introduction to image analysis. There will be opportunities for students to work with different microscopes on campus in Core Facilities and Investigator laboratories. Since this is the first time this course has been offered, we will be actively seeking input from the students on topics and course format. This will give the students the chance to increase the usefulness of this course for themselves, as well as future students.  Prerequisites: Graduate student in good standing at UNC typically in a biomedical, biological, or materials science. In the unlikely event that space is limited, preference will be given to Neuroscience and Cell Biology & Physiology graduate students. Limit on Enrollment and Priority for Registration: In order to create a climate for active discussion and exploration of the material, enrollment will be capped to 12 students.  All students are required to obtain permission from the Course Director to enroll. Enrollment requests should describe (1) where is the student currently in their graduate career and (2) what the student hopes to learn from this class.  Priority is given to (1) students who have recently matriculated into the Cell Biology and Physiology Curriculum or Neuroscience Curriculum, and to (2) graduate students from other departments or programs who are working in labs conducting microscopy research. Course Organization and Style: Each week there will be a class period including lecture style presentations and classroom discussions.  There will also be a lab period each week including either hands-on microscopy techniques or analysis examples. There will also be an independent project that the student will include project design, acquiring and analyzing microscopy data, and presenting the findings to the class. This class is 3 units of credit and satisfies the Neuroscience elective requirement. For assistance with enrolling, please contact Janice Warfford, janice_warfford@med.unc.edu. Course Directors:  Michelle Itano, itano@unc.edu; James Bear, jbear@email.unc.edu. Meeting Times: Spring Semester, 2020; ~1 hr of lecture/classroom activities and ~2 hrs of hands-on microscopy/analysis lab activities each week; March-April (6-8 weeks total) Exact scheduling details will be based upon the availability of enrolled students