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Monday – FUSION: Max Hockenberry & Christina So
August 25, 2025 @ 12:30 pm - 1:30 pm
Max Hockenberry (Bear and Legant labs)
- We have developed an imaging based approach to directly visualize the motion of single molecules of actin and the arp2/3 complex in living cells.
- We have used this approach and preliminary data to assess how molecules of these proteins get to the front of the cell for incorporation in polymerizing actin networks at the leading edge.
Christina So (Neher lab)
- ANGPTL3 and ANGPTL8 are both lipoprotein inhibitors that form a complex in the cell prior to secretion. When not in complex, ANGPTL8 gets trafficked to lysosomes, and it is unknown how ANGPTL3 diverts ANGPTL8 from lysosomes.