• FUSION Seminar Series

    Monday – FUSION: Garrett Sessions & Anca Frasineanu

    G202 MBRB 111 Mason Farm Rd, Chapel Hill

    Garrett Sessions (Purvis & Diekman labs) Aggregate analysis of cellular senescence fails to identify the effect of key subpopulations Senescence induction is heterogeneous over time, making time point selection critical for designing future experiments   Anca Frasineanu (Gupton lab) TRIM9 deletion decreases mitochondrial translation and increases nuclear speckle proteins in the PSD proteome of 6-month-old … Read more

  • Monday – FUSION: Jocelyn Alvarado & Max Hockenberry

    G202 MBRB 111 Mason Farm Rd, Chapel Hill

    Jocelyn Alvarado (Campbell lab) Characterizing the effect of increasing levels of metavinculin on force transmission in MEFs at the general cellular level and at local focal adhesions   Max Hockenberry (Bear and Legant labs) Developing a method to quantitatively measure the traction forces produced by cells migrating in any arbitrary 3D geometry Applying this methodology … Read more

  • Monday – FUSION: Matt Zimmerman & Nicole Hondrogiannis

    G202 MBRB 111 Mason Farm Rd, Chapel Hill

    Matt Zimmerman (Miller lab) FRb inhibits macrophage survival and suppresses anti-tumor functions in vitro FRb ablation decreases tumor growth in preliminary experiments   Nicole Hondrogiannis (Deshmukh lab) Neurons are long-lived post mitotic cells Exploring if the apoptotic pathway in neurons becomes activated in response to sublethal DNA damage

  • FUSION Seminar Series

    Monday – FUSION: Ian McCabe & Mark Hazelbaker

    G202 MBRB 111 Mason Farm Rd, Chapel Hill

    Ian McCabe (Yeh lab) Identifying two clinically relevant populations of CAFs in PDAC: tumor promoting (proCAF) and tumor restrictive (restCAF) These CAF subtypes are distributed spatially and may play distinct functional roles Mark Hazelbaker (Bear lab) The Arp2/3 complex is required for the turnover of clathrin plaques ACK regulates the recruitment of the Arp2/3 complex … Read more