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Event Series FUSION Seminar Series

Monday – FUSION: Garrett Sessions & Anca Frasineanu

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Garrett Sessions (Purvis & Diekman labs) Aggregate analysis of cellular senescence fails to identify the effect of key subpopulations Senescence induction is heterogeneous over time, making time point selection critical for designing future experiments   Anca Frasineanu (Gupton lab) TRIM9 deletion decreases mitochondrial translation and increases nuclear speckle proteins in the PSD proteome of 6-month-old … Read more

Monday – FUSION: Jocelyn Alvarado & Max Hockenberry

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Jocelyn Alvarado (Campbell lab) Characterizing the effect of increasing levels of metavinculin on force transmission in MEFs at the general cellular level and at local focal adhesions   Max Hockenberry (Bear and Legant labs) Developing a method to quantitatively measure the traction forces produced by cells migrating in any arbitrary 3D geometry Applying this methodology … Read more

Monday – FUSION: Matt Zimmerman & Nicole Hondrogiannis

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Matt Zimmerman (Miller lab) FRb inhibits macrophage survival and suppresses anti-tumor functions in vitro FRb ablation decreases tumor growth in preliminary experiments   Nicole Hondrogiannis (Deshmukh lab) Neurons are long-lived post mitotic cells Exploring if the apoptotic pathway in neurons becomes activated in response to sublethal DNA damage

Event Series FUSION Seminar Series

Monday – FUSION: Ian McCabe & Mark Hazelbaker

G202 MBRB 111 Mason Farm Rd, Chapel Hill

Ian McCabe (Yeh lab) Identifying two clinically relevant populations of CAFs in PDAC: tumor promoting (proCAF) and tumor restrictive (restCAF) These CAF subtypes are distributed spatially and may play distinct functional roles Mark Hazelbaker (Bear lab) The Arp2/3 complex is required for the turnover of clathrin plaques ACK regulates the recruitment of the Arp2/3 complex … Read more

Event Series FUSION Seminar Series

Monday – FUSION: David Rocco & Andrew Kennedy

G202 MBRB 111 Mason Farm Rd, Chapel Hill

David Rocco (Bergmeier lab) Elucidating a novel pathway for platelet activation Understanding how this pathway contributes to platelet adhesion under arterial shear stress   Andrew Kennedy (Thaxton lab) ER sheet dynamics are distended in T cells in solid cancers Balancing ER sheets and tubules may protect T cells from disturbed ER dynamics in solid tumors