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Department Chair
Professor
UNC-Chapel Hill

Education and Training

Emory University, BS/BA, 1992
Duke University, PhD, 1997
University of North Carolina at Chapel Hill, Postdoctoral, 1997-2003

Areas of Interest

Studies in the Caron Lab are focused on elucidating unique G protein-coupled receptor pathways that are important for the development and function of the cardiovascular system. Using a variety of gene-targeted animal models in conjunction with state-of-the-art in vitro cell biological systems, we have discovered fundamental roles for several secretin- and chemokine-family receptors in cardiovascular development and disease. Much of our recent work has focused on the pivotal roles that RAMPs (receptor activity-modifying proteins) play in controlling receptor function, cellular signaling, and physiology. The importance of the RAMP-receptor interaction is best exemplified by our work centered on the small blood protein, adrenomedullin – a potent lymphangiogenic vasodilator that serves as a strong prognostic indicator for many disease conditions.

 

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Affliations

Cell Biology and Physiology Curriculum
Department of Genetics
UNC McAllister Heart Institute
Lineberger Comprehensive Cancer Center
Curriculum in Genetics and Molecular Biology
Integrative Vascular Biology Program
Developmental Biology Program

Katheen Caron, PhD