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Welcome to the Advanced Analytics Core

The CGIBD’s Advanced Analytics (AA) Core provides high-quality, quantitative solutions for studying proteins and nucleic acids at the bulk or single-cell level. Whether measuring gene expression, cytokines, or other biomarkers, the AA Core offers cost-effective access to a wide range of assays and an extensive probe library through a unique cost-sharing model. In addition to molecular analysis, the AA Core now provides services for epithelial organoid and 2D monolayer cultures (EpCultures)—powerful in vitro models for studying the gastrointestinal tract. Developed at UNC, these platforms offer critical physiological relevance but can be costly and technically challenging to implement. By offering optimized protocols, essential reagents, and expert support, the AA Core makes EpCultures more accessible, enabling investigators to integrate these advanced models into their research more easily.

Genomics Services

High-throughput PCR (Fluidigm/Standard BioTools BioMark HD)

–Gene Expression qPCR, SNP Genotyping, Copy Number Variation, Digital PCR

Library Preparation, Sequencing, and Basic Data Processing (10x Genomics Chromium, Fluidigm/Standard BioTools C1)

–RNA-Seq, DNA-Seq, ATAC-Seq, CITE-Seq, REAP-Seq

Protein Detection (Protein Simple Milo)

–Single Cell Western Blot

Cell sorting (FACS) – Available in conjunction with our other single cell services

EpCulture Services

Conditioned Media (WRN and more)

Multi-Well Cell Expansion

2D/3D Organoid Generation

Gene Editing

Experimental Design Consultation

Training

 

Acknowledgement

We appreciate the opportunity to support your research. The Advanced Analytics Core is funded through the the CGIBD’s center grant. To help us track the scientific impact of our work and secure continued funding, we kindly ask investigators to acknowledge the core in publications that include data generated through our services. Proper citation allows us to demonstrate our contributions to research and sustain high-quality support for the scientific community.

If your work includes data from our core, please cite our center grant: P30 DK034987 in your acknowledgments. Additionally, we would appreciate it if you shared a link to your publication with us at aacore.med.unc.edu.

 

Contacts:

Gabrielle Cannon
Genomic Services Manager
Center for Gastrointestinal Biology and Disease
111 Mason Farm Rd, 4331 MBRB, CB# 7032
Chapel Hill, NC, 27599
(919) 966-0175

Quinn Fong
Research Specialist, EpCultures
Center for Gastrointestinal Biology and Disease
111 Mason Farm Rd, 4331 MBRB, CB# 7032
Chapel Hill, NC, 27599
(919) 966-0175

Carlton Anderson, Director of Operations
Research Specialist, FACS
Center for Gastrointestinal Biology and Disease
111 Mason Farm Rd, 4331 MBRB, CB# 7032
Chapel Hill, NC, 27599
(919) 966-0175

Nikki McCoy, Assistant Director
Research Specialist
Center for Gastrointestinal Biology and Disease
111 Mason Farm Rd, 4331 MBRB, CB# 7032
Chapel Hill, NC, 27599
(919) 966-0175

Scott Magness, PhD, Faculty Advisor
Associate Professor
Departments of Medicine, Biomedical Engineering, and Cell & Molecular Physiology
Division of Gastroenterology and Hepatology
101A Mason Farm Rd, 4337 MBRB, CB# 7032
Chapel Hill, NC, 27599
(919) 966-6816
www.magnesslab.org