The Animal Metabolism Phenotyping Core offers technical support and expertise for measuring traits related to metabolism in mouse models of nutrition and disease. The core provides access to state-of-the-art methods and equipment to support high quality phenotyping of energy balance in mice.
Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.
Cognitive flexibility, which refers to the brain’s ability to switch between mental processes in response to external stimuli and different task demands, seems to begin developing during the first two years of life, which is much earlier than previously thought. UNC BRIC researchers led by Weili Lin, PhD, used magnetic resonance imaging techniques to show … Continued
In a recent Chan Zuckerberg Science Initiative (CZI) newsletter, Dr. Itano was recognized for her work facilitating collaborations between researchers and computing specialists to design and disseminate efficient bioimaging pipelines at UNC and for leading more than 90 individual training sessions for new users on microscopes in the Neuroscience Microscopy Core.
The Precision Nutrition Core now offers the QuantStudio 12K Flex Real-Time PCR System—a highly flexible, comprehensive real-time PCR platform that can genotype or quantify gene expression in a customized and targeted approach. The system can accommodate OpenArray plates, TaqMan® array cards, 384-well, 96-well, and FAST 96-well plates, allowing us to select the format that is … Continued