The UNC HTPSA is housed in the Genetic Medicine Building and equipped for providing high quality peptide synthesis, peptide arrays and microarrays, and peptide library synthesis.

PTI Symphony Multiple Peptide Synthesizer

symphony3.jpg

Specifications

  • Simultaneous synthesis of up to 12 peptides
  • Totally independent synthesis of each peptide
  • All reagents and synthesis cycles in inert atmosphere
  • Synthesis scale from 0.005 to 1.2 mmol

CEM Liberty Blue Microwave Peptide Synthesizer

Specifications

  • Fast peptide synthesis (4 min per residue)
  • Totally automated synthesis of peptides containing unnatural amino acids
  • Synthesis of high purity long and difficult to make peptides
  • All reagents and synthesis cycles in inert atmosphere
  • Synthesis scale from 0.005 to 5 mmol

PTI PS-3 Peptide Synthesizer

PS3.jpg

Specifications

  • Synthesizes up to 3 peptides (sequentially)
  • All reagents and synthesis cycles in inert atmosphere
  • Synthesis scale from 0.01 to 0.75 mmol
  • Tray capacity of 45 amino acid vials

Waters 2545 preparative HPLC system

Waters2545_HPLC.jpg Specifications

  • Flow rates up to 150 ml/min
  • Dual wavelength UV detector
  • Injection volume up to 5 ml (or unlimited)
  • Sophisticated fraction collector with several task-specific sample run modes (time, signal, peak numbers, etc.)

Waters 1525 semi-prep HPLC system

Waters1525_HPLC.jpg Specifications

  • Flow rates up to 22.5 ml/min
  • Photodiode Array detector
  • Injection volume up to 2.5 ml
  • HPLC Software controlled fraction collector

Waters Alliance HPLC system

WatersAlliance_HPLC.jpg Specifications

  • Flow rate up 50 µl to 5 ml per minute
  • Dual wavelength UV detector
  • Injection volume 1 to 100 µl
  • Samples and column temperature control with auto sampler

Mettler Toledo XP26 DeltaRange Microbalance

MettlerXP26_Balance.jpg Specifications

  • d = 2 µg for range 0 – 5.1 g
  • d = 10 µg for range 5.1 – 22 g
  • large size of weighing pan
  • electrostatic charges eliminated from samples and containers by use of high voltage U-electrode

GeneMachines OmniGrid 100 Microarray Printer

OmniGrid_microarray.jpg

Specifications

  • multi-axis robot that is capable of arraying samples from standard 384-well sample plates onto up to 100 microscope slides
  • up to 4600 spots per slide
  • spot size 0.2 mm (~2 nl sample per spot)

Two VirTis BenchTop Lyophilizers with Speed-Vac

Picture of VirTis BenchTop™ “K” Series Specifications

  • low temperature lyophilizers suitable to use
    with water/acetonitrile mixtures
  • speed-vac up to 40 samples (Eppendorf tubes) per cycle