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UNC Genetics PublicationsDepartment of Genetics faculty, postdocs, students and collaborators published 8 papers during August 4th – 17th, 2024.

Reliable estimation of tree branch lengths using deep neural networks. 

Suvorov A, Schrider DR.

PLoS Comput Biol. 2024 Aug 5;20(8):e1012337. doi: 10.1371/journal.pcbi.1012337. eCollection 2024 Aug.

PMID: 39102450

 

Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia. 

Chang TC, Chen W, Qu C, Cheng Z, Hedges D, Elsayed A, Pounds SB, Shago M, Rabin KR, Raetz EA, Devidas M, Cheng C, Angiolillo A, Baviskar P, Borowitz M, Burke MJ, Carroll A, Carroll WL, Chen IM, Harvey R, Heerema N, Iacobucci I, Wang JR, Jeha S, Larsen E, Mattano L, Maloney K, Pui CH, Ramirez NC, Salzer W, Willman C, Winick N, Wood B, Hunger SP, Wu G, Mullighan CG, Loh ML.

J Clin Oncol. 2024 Aug 9:JCO2302238. doi: 10.1200/JCO.23.02238. Online ahead of print.

PMID: 39121442

 

Poor prognosis among radiation associated bladder cancer is defined by clinicogenomic features. 

Wijetunga NA, Gessner KH, Kanchi K, Moore JA, Fleischmann Z, Jin DX, Frampton GM, Sturdivant M, Repka M, Sud S, Corcoran DL, Galsky MD, Milowsky MI, Wobker SE, Kim WY, Rose TL, Damrauer JS.

Cancer Res Commun. 2024 Aug 8. doi: 10.1158/2767-9764.CRC-24-0352. Online ahead of print.

PMID: 39113632

 

EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth. 

Corbin J, Yu X, Jin J, Cai L, Wang GG.

Oncogene. 2024 Aug 7. doi: 10.1038/s41388-024-03119-9. Online ahead of print.

PMID: 39112519

 

Grandparents’ educational attainment is associated with grandchildren’s epigenetic-based age acceleration in the National Growth and Health Study. 

Surachman A, Hamlat E, Zannas AS, Horvath S, Laraia B, Epel E.

Soc Sci Med. 2024 Jul 14;355:117142. doi: 10.1016/j.socscimed.2024.117142. Epub 2024 Jul 14.

PMID: 39106784

 

Exploring the impact of somatic variant burden on seizures in focal cortical dysplasia. 

Gade M, Heinzen EL.

Brain. 2024 Aug 5:awae247. doi: 10.1093/brain/awae247. Online ahead of print.

PMID: 39101458 No abstract available.

 

Disease severity drives risk of venous thrombotic events in women with sickle cell disease in a single-center retrospective study. 

Light J, Abrams CM, Ilich A, Huang S, Zhu H, Baskin-Miller J, Sparkenbaugh EM.

Res Pract Thromb Haemost. 2024 Jun 10;8(4):102471. doi: 10.1016/j.rpth.2024.102471. eCollection 2024 May.

PMID: 39099800 Free PMC article.

 

Equitable Care for Patients With Disabilities: Considerations for the Gynecologic Health Care Professional. 

Meredith S, Dolan S, Kuppermann M, Talati A, Ayers K, Michie M, Stoll K.

Obstet Gynecol. 2024 Sep 1;144(3):e56. doi: 10.1097/AOG.0000000000005683.

PMID: 39146544 No abstract available.