Department of Genetics Publications for July 1-14, 2018

Department of Genetics faculty, postdocs, students and collaborators published nine papers during July 1-14, 2018.

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.

Story Jovanova O, Nedeljkovic I, Derek S, Walker RM, Liu C, Luciano M, Bressler J, Brody J, Drake AJ, Evans KL, Gondalia R, Kunze S, Kuhnel B, Lahti J, Lemaitre RN, Marioni RE, Swenson B, Himali JJ, Wu H, Li Y, McRae AF, Russ TC, Stewart J, Wang Z, Zhang G, Ladwig KH, Uitterlinden AG, Guo X, Peters A, Räikkönen K, Starr JM, Waldenberger M, Wray NR, Whitsel EA, Sotoodehnia N, Seshadri S, Porteous DJ, van Meurs J, Mosley TH, McIntosh AM, Mendelson MM, Levy D, Hou L, Eriksson JG, Fornage M, Deary IJ, Baccarelli A, Tiemeier H, Amin N.

JAMA Psychiatry. 2018 Jul 11. doi: 10.1001/jamapsychiatry.2018.1725. [Epub ahead of print]

PMID: 29998287

Intrinsic molecular subtypes of breast cancers categorized as HER2-positive using an alternative chromosome 17 probe assay.

Desai NV, Torous V, Parker J, Auman JT, Rosson GB, Cruz C, Perou CM, Schnitt SJ, Tung N.

Breast Cancer Res. 2018 Jul 11;20(1):75. doi: 10.1186/s13058-018-1005-z.

PMID: 29996866

Navigating the nuances of clinical sequence variant interpretation in Mendelian disease.

Strande NT, Brnich SE, Roman TS, Berg JS.

Genet Med. 2018 Jul 10. doi: 10.1038/s41436-018-0100-y. [Epub ahead of print] Review.

PMID: 29988079

Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.

Gorlov I, Orlow I, Ringelberg C, Hernando E, Ernstoff MS, Cheng C, Her S, Parker JS, Thompson CL, Gerstenblith MR, Berwick M, Amos C.

Melanoma Res. 2018 Jul 2. doi: 10.1097/CMR.0000000000000473. [Epub ahead of print]

PMID: 29975213

RIG-I Detects Kaposi’s Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner.

Zhang Y, Dittmer DP, Mieczkowski PA, Host KM, Fusco WG, Duncan JA, Damania B.

MBio. 2018 Jul 3;9(4). pii: e00823-18. doi: 10.1128/mBio.00823-18.

PMID: 29970461

Single-cell analysis of early progenitor cells that build coronary arteries.

Su T, Stanley G, Sinha R, D’Amato G, Das S, Rhee S, Chang AH, Poduri A, Raftrey B, Dinh TT, Roper WA, Li G, Quinn KE, Caron KM, Wu S, Miquerol L, Butcher EC, Weissman I, Quake S, Red-Horse K.

Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0288-7. [Epub ahead of print]

PMID: 29973725

Polybromo-1 (PBRM1) bromodomains variably influence nucleosome interactions and cellular function.

Slaughter MJ, Shanle EK, McFadden AW, Hollis ES, Suttle LE, Strahl BD, Davis IJ.

J Biol Chem. 2018 Jul 9. pii: jbc.RA118.003381. doi: 10.1074/jbc.RA118.003381. [Epub ahead of print]

PMID: 29986887

 Heritability of Regional Brain Volumes in Large-Scale Neuroimaging and Genetic Studies.

Zhao B, Ibrahim JG, Li Y, Li T, Wang Y, Shan Y, Zhu Z, Zhou F, Zhang J, Huang C, Liao H, Yang L, Thompson PM, Zhu H.

Cereb Cortex. 2018 Jul 12. doi: 10.1093/cercor/bhy157. [Epub ahead of print]

PMID:  30010813

STEPS: an efficient prospective likelihood approach to genetic association analyses of secondary traits in extreme phenotype sequencing.

Bi W, Li Y, Smeltzer MP, Gao G, Zhao S, Kang G.

Biostatistics. 2018 Jul 11. doi: 10.1093/biostatistics/kxy030. [Epub ahead of print]

PMID:  30007308