Department of Genetics faculty, postdocs, students and collaborators published four papers during June 30 – July 13, 2019.

 

Selective serotonin reuptake inhibitors ameliorate MEGF10 myopathy.
Saha M, Rizzo SA, Ramanathan M, Hightower RM, Santostefano KE, Terada N, Finkel RS, Berg JS, Chahin N, Pacak CA, Wagner RE, Alexander MS, Draper I, Kang PB.
Hum Mol Genet. 2019 Jul 15;28(14):2365-2377. doi: 10.1093/hmg/ddz064.
PMID: 31267131

 

lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA.
Schertzer MD, Braceros KCA, Starmer J, Cherney RE, Lee DM, Salazar G, Justice M, Bischoff SR, Cowley DO, Ariel P, Zylka MJ, Dowen JM, Magnuson T, Calabrese JM.
Mol Cell. 2019 Jun 27. pii: S1097-2765(19)30400-9. doi: 10.1016/j.molcel.2019.05.028. [Epub ahead of print]
PMID: 31256989

 

Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding.
Rossi MA, Basiri ML, McHenry JA, Kosyk O, Otis JM, van den Munkhof HE, Bryois J, Hübel C, Breen G, Guo W, Bulik CM, Sullivan PF, Stuber GD.
Science. 2019 Jun 28;364(6447):1271-1274. doi: 10.1126/science.aax1184.
PMID: 31249056

 

Consistency and overfitting of multi-omics methods on experimental data.
McCabe SD, Lin DY, Love MI.
Brief Bioinform. 2019 Jul 4. pii: bbz070. doi: 10.1093/bib/bbz070. [Epub ahead of print]
PMID: 31281919