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Department of Genetics faculty, postdocs, students and collaborators published nine papers during Oct. 21 – Nov. 3, 2018.

Deciphering the Emerging Complexities of Molecular Mechanisms at GWAS Loci.

Cannon ME, Mohlke KL.

Am J Hum Genet. 2018 Nov 1;103(5):637-653. doi: 10.1016/j.ajhg.2018.10.001. Review.

PMID: 30388398

Tumor mutational burden is a determinant of immune-mediated survival in breast cancer.

Thomas A, Routh ED, Pullikuth A, Jin G, Su J, Chou JW, Hoadley KA, Print C, Knowlton N, Black MA, Demaria S, Wang E, Bedognetti D, Jones WD, Mehta GA, Gatza ML, Perou CM, Page DB, Triozzi P, Miller LD.

Oncoimmunology. 2018 Jul 30;7(10):e1490854. doi: 10.1080/2162402X.2018.1490854. eCollection 2018.

PMID: 30386679

A spike in inflammation.

Johnson BM, Junkins RD, Ting JP.

Nat Nanotechnol. 2018 Oct 29. doi: 10.1038/s41565-018-0292-y. [Epub ahead of print] No abstract available.

PMID: 30374158

IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model.

Zwarycz B, Gracz AD, Rivera KR, Williamson IA, Samsa LA, Starmer J, Daniele MA, Salter-Cid L, Zhao Q, Magness ST.

Cell Mol Gastroenterol Hepatol. 2018 Jul 4;7(1):1-17. doi: 10.1016/j.jcmgh.2018.06.008. eCollection 2019.

PMID: 30364840

FMLRC: Hybrid long read error correction using an FM-index.

Wang JR, Holt J, McMillan L, Jones CD.

BMC Bioinformatics. 2018 Feb 9;19(1):50. doi: 10.1186/s12859-018-2051-3.

PMID: 29426289

Swimming downstream: statistical analysis of differential transcript usage following Salmon quantification.

Love MI, Soneson C, Patro R.

F1000Res. 2018 Jun 27;7:952. doi: 10.12688/f1000research.15398.1. eCollection 2018.

PMID: 30356428

Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions.

Xu W, Wittchen ES, Hoopes SL, Stefanini L, Burridge K, Caron KM.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2410-2422. doi: 10.1161/ATVBAHA.118.311645.

PMID: 30354217

Evolutionarily conserved <i>Tbx5</i>-<i>Wnt2/2b</i> pathway orchestrates cardiopulmonary development.

Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP.

Proc Natl Acad Sci U S A. 2018 Oct 23. pii: 201811624. doi: 10.1073/pnas.1811624115. [Epub ahead of print]

PMID: 30352852

Fate mapping during regeneration: cells that undergo compensatory proliferation in damaged Drosophila eye imaginal discs differentiate into multiple retinal accessory cell types.

Meserve JH, Duronio RJ.

Dev Biol. 2018 Oct 19. pii: S0012-1606(18)30438-X. doi: 10.1016/j.ydbio.2018.10.011. [Epub ahead of print]

PMID: 30347187