Department of Genetics faculty, postdocs, students and collaborators published five papers during May 5-18, 2019.

 

The immune microenvironment in hormone receptor-positive breast cancer before and after preoperative chemotherapy.
Waks AG, Stover DG, Guerriero JL, Dillon DA, Barry WT, Gjini E, Hartl CA, Lo WT, Savoie J, Brock J, Wesolowski R, Li Z, Damicis A, Philips AV, Wu Y, Yang F, Sullivan A, Danaher P, Brauer HA, Osmani W, Lipschitz M, Hoadley KA, Goldberg MS, Perou CM, Rodig S, Winer EP, Krop I, Mittendorf EA, Tolaney SM.
Clin Cancer Res. 2019 May 6. pii: clincanres.0173.2019. doi: 10.1158/1078-0432.CCR-19-0173. [Epub ahead of print]
PMID: 31061067

 

Multi-SNP mediation intersection-union test.
Zhong W, Spracklen CN, Mohlke KL, Zheng X, Fine J, Li Y.
Bioinformatics. 2019 Apr 25. pii: btz285. doi: 10.1093/bioinformatics/btz285. [Epub ahead of print]
PMID: 31099385

 

Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin.
Minrovic BM, Hubble VB, Barker WT, Jania LA, Melander RJ, Koller BH, Melander C.
ACS Med Chem Lett. 2019 Apr 17;10(5):828-833. doi: 10.1021/acsmedchemlett.9b00135. eCollection 2019 May 9.
PMID: 31098007

 

 

FUT2 Variants Confer Susceptibility to Familial Otitis Media.
Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM; University of Washington Center for Mendelian Genomics (UWCMG), Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafrén L, Chonmaitree T, Sale MM, Ahmed ZM.
Am J Hum Genet. 2018 Nov 1;103(5):679-690. doi: 10.1016/j.ajhg.2018.09.010. Epub 2018 Oct 25.
PMID: 30401457

 

A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies.
Gunasekara DB, Speer J, Wang Y, Nguyen DL, Reed MI, Smiddy NM, Parker JS, Fallon JK, Smith PC, Sims CE, Magness ST, Allbritton NL.
Anal Chem. 2018 Nov 20;90(22):13331-13340. doi: 10.1021/acs.analchem.8b02845. Epub 2018 Oct 30.
PMID: 30350627