Research Interests
Key words: Developmental genomics
Research in the lab focuses on how a single genome gives rise to a variety of cell types and body parts during development. We use Drosophila as a model organism to investigate (1) how transcription factors access DNA to regulate complex patterns of gene expression, and (2) how post-translational modification of histones contributes to maintenance of gene expression programs over time. We combine genomic approaches (e.g. chromatin immunoprecipitation followed by high-throughput sequencing) withDrosophila genetics and transgenesis to address both of these questions. Defects in cell fate specification and maintenance of cell identity often occur in human diseases, including cancer.
Dan McKay in UNC Genetics News
October 5, 2020
Department of Genetics Publications for September 20 – October 3, 2020
Department of Genetics faculty, postdocs, students and collaborators published seven papers during Sept. 20 – Oct. 3, 2020.
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August 21, 2020
#BlackinGenetics Attracts National Attention
GMB student Alexis Stutzman and Markia Smith start a movement.
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June 15, 2020
Department of Genetics Publications for May 31 – June 13, 2020
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during May 31 – June 13, 2020.
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March 10, 2020
Department of Genetics Publications for Feb. 23 – March 7, 2020
Department of Genetics faculty, postdocs, students and collaborators published fourteen papers during Feb. 23 – March 7, 2020.
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September 9, 2019
Department of Genetics Publications for August 25 – September 7, 2019
Department of Genetics faculty, postdocs, students and collaborators published four papers during Aug. 25 – Sept. 7, 2019.
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July 8, 2019
Department of Genetics Publications for June 16-29, 2019
Department of Genetics faculty, postdocs, students and collaborators published five papers during June 16-29, 2019.
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May 6, 2019
Department of Genetics Publications from April 21-May 4, 2019
Department of Genetics faculty, postdocs, students and collaborators published fourteen papers during April 21-May 4, 2019.
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August 13, 2018
Department of Genetics Publications for July 29 – Aug. 11, 2018
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during July 29 – Aug. 11, 2018.
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May 30, 2017
Department of Genetics Faculty Publications for May 13-27, 2017
Department of Genetics faculty and collaborators published twenty papers during the second half of May 2017. Prenatal exome sequencing in anomalous fetuses: new opportunities and challenges. Vora NL, Powell B, Brandt A, Strande N, Hardisty E, Gilmore K, Foreman AKM, Wilhelmsen K, Bizon C, Reilly J, Owen P, Powell CM, Skinner D, Rini C, Lyerly …
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November 7, 2016
Genetics Faculty Publications for Oct 15 – Nov 4, 2016
During the last three weeks, Department of Genetics faculty members, along with their colleagues, have published 21 manuscripts on a wide variety of topics. A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories. O’Daniel JM, McLaughlin HM, Amendola LM, Bale SJ, Berg JS, Bick D, Bowling KM, Chao …
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