Department of Genetics Publications for November 10th – 23rd, 2024

Department of Genetics faculty, postdocs, students and collaborators published 19 papers during November 10th – 23rd, 2024.

 

The chosen few: Mycobacterium tuberculosis isolates for IMPAc-TB. 

Larsen SE, Abdelaal HFM, Plumlee CR, Cohen SB, Kim HD, Barrett HW, Liu Q, Harband MH, Berube BJ, Baldwin SL, Fortune SM, Urdahl KB, Coler RN.

Front Immunol. 2024 Oct 28;15:1427510. doi: 10.3389/fimmu.2024.1427510. eCollection 2024.

PMID: 39530100 Free PMC article. Review.

 

Genome-wide copy number variation association study in anorexia nervosa. 

Walker A, Karlsson R, Szatkiewicz JP, Thornton LM, Yilmaz Z, Leppä VM, Savva A, Lin T, Sidorenko J, McRae A, Kirov G, Davies HL, Fundín BT, Chawner SJRA, Song J, Borg S, Wen J, Watson HJ, Munn-Chernoff MA, Baker JH, Gordon S, Berrettini WH, Brandt H, Crawford S, Halmi KA, Kaplan AS, Kaye WH, Mitchell J, Strober M, Woodside DB, Pedersen NL, Parker R, Jordan J, Kennedy MA, Birgegård A, Landén M, Martin NG, Sullivan PF, Bulik CM, Wray NR.

Mol Psychiatry. 2024 Nov 12. doi: 10.1038/s41380-024-02811-2. Online ahead of print.

PMID: 39533101

 

Piwi mutant germ cells transmit a form of heritable stress that promotes longevity. 

Heestand B, McCarthy B, Simon M, Lister-Shimauchi EH, Frenk S, Ahmed S.

Aging Cell. 2024 Nov 9:e14350. doi: 10.1111/acel.14350. Online ahead of print.

PMID: 39520150

 

Mpox surveillance: the need for enhanced testing and genomic epidemiology. 

Wang JR.

Lancet. 2024 Nov 9;404(10465):1784-1785. doi: 10.1016/S0140-6736(24)02386-9.

PMID: 39521500 No abstract available.

 

DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance. 

Conway K, Edmiston SN, Vondras A, Reiner A, Corcoran DL, Shen R, Parrish EA, Hao H, Lin L, Kenney JM, Ilelaboye G, Kostrzewa CE, Kuan PF, Busam KJ, Lezcano C, Lee TK, Hernando E, Googe PB, Ollila DW, Moschos S, Gorlov I, Amos CI, Ernstoff MS, Cust AE, Wilmott JS, Scolyer RA, Mann GJ, Vergara IA, Ko J, Rees JR, Yan S, Nagore E, Bosenberg M, Rothberg BG, Osman I, Lee JE, Saenger Y, Bogner P, Thompson CL, Gerstenblith M, Holmen SL, Funchain P, Brunsgaard E, Depcik-Smith ND, Luo L, Boyce T, Orlow I, Begg CB, Berwick M, Thomas NE; InterMEL Study Group.

JCO Precis Oncol. 2024 Nov;8:e2400375. doi: 10.1200/PO-24-00375. Epub 2024 Nov 7.

PMID: 39509669

 

Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies. 

Zhang D, Gao B, Feng Q, Manichaikul A, Peloso GM, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Gabriel S, Gupta N, Smith JD, Aguet F, Ardlie KG, Blackwell TW, Gerszten RE, Rich SS, Rotter JI, Scott LJ, Zhou X, Lee S.

HGG Adv. 2024 Nov 13:100383. doi: 10.1016/j.xhgg.2024.100383. Online ahead of print.

PMID: 39543875

 

Joint and Individual Component Regression. 

Wang P, Wang H, Li Q, Shen D, Liu Y.

J Comput Graph Stat. 2024;33(3):763-773. doi: 10.1080/10618600.2023.2284227. Epub 2023 Dec 29.

PMID: 39526223

 

Postnatal Ovarian Transdifferentiation in the Absence of Estrogen Receptor Signaling is Dependent on Genetic Background. 

Binder AK, Burns KA, Rodriguez KF, Hamilton K, Pardo-Manuel de Villena F, Korach KS.

Endocrinology. 2024 Nov 22:bqae157. doi: 10.1210/endocr/bqae157. Online ahead of print.

PMID: 39576259

 

Using Bomb Calorimetry to Investigate Intestinal Energy Harvest in Anorexia Nervosa: Preliminary Findings on Stool Calorie Loss. 

Reed KK, Bulik-Sullivan EC, Qian Y, Javorsky E, Tarantino LM, Fodor AA, Steffen KJ, Wonderlich SA, Mehler PS, Bulik CM, Carroll IM.

Int J Eat Disord. 2024 Nov 21. doi: 10.1002/eat.24331. Online ahead of print.

PMID: 39569450

 

Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responses. 

Shirasaki T, Lenarcic E, Misumi I, Xie L, Fusco WG, Yonish B, Das A, Kim H, Cameron CE, Léger-Abraham M, Chen X, Cullen JM, Whitmire JK, Li Y, Duncan JA, Moorman NJ, Lemon SM.

Sci Adv. 2024 Nov 22;10(47):eadq6342. doi: 10.1126/sciadv.adq6342. Epub 2024 Nov 20.

PMID: 39565848 Free PMC article.

 

The PRIMED Consortium: Reducing disparities in polygenic risk assessment. 

Kullo IJ, Conomos MP, Nelson SC, Adebamowo SN, Choudhury A, Conti D, Fullerton SM, Gogarten SM, Heavner B, Hornsby WE, Kenny EE, Khan A, Khera AV, Li Y, Martin I, Mercader JM, Ng M, Raffield LM, Reiner A, Rowley R, Schaid D, Stilp A, Wiley K, Wilson R, Witte JS, Natarajan P; Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium.

Am J Hum Genet. 2024 Nov 14:S0002-9297(24)00379-3. doi: 10.1016/j.ajhg.2024.10.010. Online ahead of print.

PMID: 39561770 Review.

 

Expanded detection and impact of BAP1 alterations in cancer. 

Sturgill IR, Raab JR, Hoadley KA.

NAR Cancer. 2024 Nov 15;6(4):zcae045. doi: 10.1093/narcan/zcae045. eCollection 2024 Dec.

PMID: 39554490 Free PMC article.

 

Combination of polymeric micelle formulation of TGFβ receptor inhibitors and paclitaxel produces consistent response across different mouse models of Triple-negative breast cancer. 

Vinod N, Hwang D, Fussell SC, Owens TC, Tofade OC, Benefield TS, Copling S, Ramsey JD, Rädler PD, Atkins HM, Livingston EE, Ezzell JA, Sokolsky-Papkov M, Yuan H, Perou CM, Kabanov AV.

Bioeng Transl Med. 2024 Jun 4;9(5):e10681. doi: 10.1002/btm2.10681. eCollection 2024 Sep.

PMID: 39553439 Free PMC article.

 

Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. 

Huffman JE, Nicholas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, Emmert DB, Ghanbari M, Haessler J, Hottenga JJ, Kleber ME, Le NQ, Lee J, Lewis JP, Li-Gao R, Luan J, Malmberg A, Mangino M, Marioni RE, Martinez-Perez A, Pankratz N, Polasek O, Richmond A, Rodriguez BAT, Rotter JI, Steri M, Suchon P, Trompet S, Weiss S, Zare M, Auer P, Cho MH, Christofidou P, Davies G, de Geus E, Deleuze JF, Delgado GE, Ekunwe L, Faraday N, Gögele M, Greinacher A, Gao H, Howard T, Joshi PK, Kilpeläinen TO, Lahti J, Linneberg A, Naitza S, Noordam R, Paüls-Vergés F, Rich SS, Rosendaal FR, Rudan I, Ryan KA, Souto JC, van Rooij FJA, Wang H, Zhao W, Becker LC, Beswick A, Brown MR, Cade BE, Campbell H, Cho K, Crapo JD, Curran JE, de Maat MPM, Doyle M, Elliott P, Floyd JS, Fuchsberger C, Grarup N, Guo X, Harris SE, Hou L, Kolcic I, Kooperberg C, Menni C, Nauck M, O’Connell JR, Orrù V, Psaty BM, Räikkönen K, Smith JA, Soria JM, Stott DJ, van Hylckama Vlieg A, Watkins H, Willemsen G, Wilson PWF, Ben-Shlomo Y, Blangero J, Boomsma D, Cox SR, Dehghan A, Eriksson JG, Fiorillo E, Fornage M, Hansen T, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lange LA, März W, Mathias RA, Mitchell BD, Mook-Kanamori DO, Morange PE, Pedersen O, Pramstaller PP, Redline S, Reiner A, Ridker PM, Silverman EK, Spector TD, Völker U, Wareham NJ, Wilson JF, Yao J, Trégouët DA, Johnson AD, Wolberg AS, de Vries PS, Sabater-Lleal M, Morrison AC, Smith NL.

Blood. 2024 Nov 21;144(21):2248-2265. doi: 10.1182/blood.2023022596.

PMID: 39226462

 

Vagal stimulation ameliorates murine colitis by regulating SUMOylation. 

Youssef A, Rehman AU, Elebasy M, Roper J, Sheikh SZ, Karhausen J, Yang W, Ulloa L.

Sci Transl Med. 2024 Nov 20;16(774):eadl2184. doi: 10.1126/scitranslmed.adl2184. Epub 2024 Nov 20.

PMID: 39565873

 

Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species. 

Daigle A, Johri P.

Evolution. 2024 Nov 20:qpae168. doi: 10.1093/evolut/qpae168. Online ahead of print.

PMID: 39565285

 

Evidence for dual roles of histone H3 lysine 4 in antagonizing Polycomb group function and promoting target gene expression. 

Anyetei-Anum CS, Leatham-Jensen MP, Fox GC, Smith BR, Chirasani VR, Krajewski K, Strahl BD, Dowen JM, Matera AG, Duronio RJ, McKay DJ.

Genes Dev. 2024 Nov 19. doi: 10.1101/gad.352181.124. Online ahead of print.

PMID: 39562140

 

Endodontic access cavity training using artificial teeth and Simodont® dental trainer: A comparison of student performance and acceptance. 

Slaczka DM, Shah R, Liu C, Zou F, Karunanayake GA.

Int Endod J. 2024 Nov 18. doi: 10.1111/iej.14171. Online ahead of print.

PMID: 39555944

 

Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks. 

Stanley N, Dhawka L, Jaikumar S, Huang YC, Zannas AS.

bioRxiv [Preprint]. 2024 Nov 7:2024.10.05.616811. doi: 10.1101/2024.10.05.616811.

PMID: 39554035 Free PMC article. Preprint.