Research Interests
Key words: genetics of brain structure, neural progenitor cell models, computational biology
We are a lab exploring how variations in the genome change the structure and development of the brain, and in doing so, create risk for neuropsychiatric illness. We study genetic effects on multiple aspects of the human brain, from macroscale phenotypes like gross human brain structure measured with MRI to molecular phenotypes like gene expression and chromatin accessibility measured with genome-sequencing technologies. We also use neural progenitor cells as a modifiable and high fidelity model system to understand how disease-associated variants affect brain development.
Publications
Lab Members
If you are a grad student interested in a lab rotation, please email me. If you are interested in a postdoc in my lab, please email me with a cover letter and CV containing contact information for at least 3 references.
Jason Stein in UNC Genetics News
December 14, 2020
Department of Genetics Publications for Nov. 29 – Dec. 12, 2020
Department of Genetics faculty, postdocs, students and collaborators published ten papers during November 29 – December 12, 2020.
November 2, 2020
Department of Genetics Publications for October 11-31, 2020
Department of Genetics faculty, postdocs, students and collaborators published 18 papers during October 11-31, 2020. Survival, Pathologic Response, and Genomics in CALGB 40601 (Alliance), a Neoadjuvant Phase III Trial of Paclitaxel-Trastuzumab With or Without Lapatinib in HER2-Positive Breast Cancer. Fernandez-Martinez A, Krop IE, Hillman DW, Polley MY, Parker JS, Huebner L, Hoadley KA, …
October 5, 2020
Department of Genetics Publications for September 20 – October 3, 2020
Department of Genetics faculty, postdocs, students and collaborators published seven papers during Sept. 20 – Oct. 3, 2020.
August 10, 2020
Department of Genetics Publications for July 26 – August 8, 2020
Department of Genetics faculty, postdocs, students and staff published nine papers during July 26 – August 8, 2020.
April 6, 2020
Department of Genetics Publications for March 22 – April 4, 2020
Department of Genetics faculty, postdocs, students and collaborators published four papers during March 22 – April 4, 2020.
March 23, 2020
Department of Genetics Publications for March 8-21, 2020
Department of Genetics faculty, postdocs, students and collaborators published twelve papers during March 8-21, 2020.
November 6, 2019
Department of Genetics Publications for Oct. 20 – Nov. 2, 2019
Department of Genetics faculty, postdocs, students and collaborators published six papers during Oct. 20 – Nov. 2, 2019.
October 21, 2019
Department of Genetics Publications for October 6-19, 2019
Department of Genetics faculty, postdocs, students and collaborators published nine papers during October 6-19, 2019.
July 29, 2019
Department of Genetics Publications for July 14-27, 2019
Department of Genetics faculty, postdocs, students and collaborators published ten papers during July 14-27, 2019.
July 15, 2019
Michael Lafferty Selected for Human Genomics Program
Michael Lafferty, BCB Graduate Student in Dr. Jason Stein’s laboratory, has been selected to attend the Leena Peltonen School of Human Genomics program in Switzerland on August 18-22, 2019.
