Dr. Jesse Raab (Assistant Professor, Department of Genetics) has been awarded a five-year R35 grant from the National Institute of General Medical Sciences (NIGMS) for his project titled “Mechanisms of SWI/SNF complex assembly and function”.
The project will investigate mechanisms that combine to regulate the composition and function of SWI/SNF and determine how different functional outcomes are mediated by distinct SWI/SNF complexes. Given the critical role of SWI/SNF in development and disease, understanding how the complex is regulated to mediate different outcomes is critical for developing new approaches to targeting cancer and other diseases.