News

State of the Department FY17 A summary of the key performance indicators, accomplishments and activities of the Department of Genetics for FY17 has been posted here. UPDATE: a new link has been posted above for the State of the Department pdf that is available to everyone.

Department of Genetics faculty and collaborators published twenty papers between September 3 and 16, 2017. Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes. Nakamura J, Shimomoto T, Collins LB, Holley DW, Zhang Z, Barbee JM, Sharma V, Tian X, Kondo T, Uchida K, Yi X, Perkins DO, Willis...

Department of Genetics faculty and collaborators published eleven papers between August 20 and September 2, 2017. Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds. Makhanova N, Morgan AP, Kayashima Y, Makhanov A, Hiller S, Zhilicheva S,...

Department of Genetics faculty and collaborators published twelve papers between August 6 and August 19, 2017. Upregulation of autophagy genes and the unfolded protein response in human heart failure. Jensen BC, Bultman SJ, Holley D, Tang W, de Ridder G, Pizzo S, Bowles D, Willis MS. Int J Clin Exp...

As UNC geneticist Jonathan Berg gears up to lead a $9.7-million renewal of the NCGENES project, we look at a story from the original study and how it changed the fortunes of a woman from Goldsboro, NC. CHAPEL HILL, NC – When she was six, a mysterious ailment caused Elizabeth...

Department of Genetics faculty and collaborators published sixteen papers between July 23 and August 5. Genome-wide Association Study of Susceptibility to Particulate Matter-Associated QT Prolongation. Gondalia R, Avery CL, Napier MD, Méndez-Giráldez R, Stewart JD, Sitlani CM, Li Y, Wilhelmsen KC, Duan Q, Roach J, North KE, Reiner AP, Zhang...

Department of Genetics faculty and collaborators published six papers between July 9 and July 22. Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types. Iglesia MD, Parker JS, Hoadley KA, Serody JS, Perou CM, Vincent BG. J Natl Cancer Inst. 2016 Jun 22;108(11). doi: 10.1093/jnci/djw144. Print 2016 Nov. PMID:...

Endeavors, the UNC-Chapel Hill publication focused on research and creative activity, has published a feature article this month that describes the inception and growth of the Department of Genetics. When Fred Sanger figured out how to sequence DNA in 1975, the world changed – and so did UNC. As more...

Department of Genetics faculty and collaborators published thirteen papers during the past two weeks. Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells. Bower JJ, Vance LD, Psioda M, Smith-Roe SL, Simpson DA, Ibrahim JG, Hoadley KA, Perou CM, Kaufmann WK. NPJ Breast...

UNC and University of Florida researchers created viruses to deliver gene therapies while evading pre-existing immune system responses. Aravind Asokan, PhD, led the research team at UNC. June 15, 2017 CHAPEL HILL, NC – For many patients, participating in gene therapy clinical trials isn’t an option because their immune system...