Dr. Yuchao Jiang (Assistant Professor of Biostatistics and Genetics) was awarded an R35 grant from the National Institute of General Medical Sciences (NIGMS) for his project titled “Statistical Methods for Bulk-Tissue and Single-Cell Multi-Omics Integration”. The program will focus on the following interconnected objectives: (i) bulk omics deconvolution aided by single-cell sequencing, followed by association testing with clinical variables; (ii) joint modeling of bulk genomic sequencing and single-cell transcriptomic sequencing data to simultaneously infer DNA and RNA variation at the single-cell level; and (iii) multi-modal alignment of single-cell omics data. The long-term vision is to introduce problems arising from new biomedical data to the statistics community and to provide data-driven statistical methods and open-source tools to biomedical researchers for better data analysis and experimental design.