Category: Research
UNC Hematology and Lineberger Faculty Published a Study on Anti-CD30 CAR T-Cell Therapy in High-Risk Lymphoma Patients
This new study highlights safety and efficacy of Anti-CD30 CAR T-Cell therapy in high-risk lymphoma patients A team comprised mainly of faculty from the Division of Hematology and UNC Lineberger Comprehensive Cancer Center published a groundbreaking phase 1 study in The Lancet Haematology. The study demonstrates the safety and promising activity of anti-CD30 CAR T cells as consol … Read more
Dr. Akulian Leading Study of AI-Based Image Analysis Module for Lung Cancer
Jason Akulian, MD, PhD, associate professor of medicine in the UNC Division of Pulmonary & Critical Care Medicine, will lead research efforts aimed to advance AI-driven lung cancer detection through bronchoscopy. Researchers at the University of North Carolina will study an AI-based image analysis module for lung cancer through the ON-SITE study. The multicenter study in bro … Read more
Wearable Devices Can Increase Health Anxiety. Could They Adversely Affect Health?
For patients with atrial fibrillation, using a wearable device can lead to higher rates of anxiety about their Afib symptoms and treatment, doctor visits, and use of informal healthcare resources, according to a new study from UNC School of Medicine researchers led by Lindsey Rosman, PhD. Lindsey A. Rosman, PhD Using a wearable device, such as a smart watch, to track health data … Read more
Dr. Jason Akulian Leads First Clinical Research Site to Test Innovative Pleural Effusion Care
In collaboration with the company Pleural Dynamics, UNC School of Medicine researchers led by Jason Akulian, MD, associate professor in the Department of Medicine, are the first to use a fully implantable automatic effusion shunt with no external catheters or expensive drainage canisters to provide an innovative new option for patients who struggle with chronic fluid collection. … Read more
Metformin Use Shows No Increase in Gastrointestinal Adverse Events During GLP-1RA Initiation
A recent study analyzing data from four pivotal clinical trials—LEADER, STEP 2, SUSTAIN 6, and PIONEER 6—evaluated the impact of concomitant metformin use on gastrointestinal adverse events during the initiation and titration of glucagon-like peptide 1 receptor agonists (GLP-1RA). Klara Klein, MD, PhD Klara Klein, MD, PhD, assistant professor of medicine in the UNC Division of En … Read more
Removing the Penicillin Allergic Label: Researchers Introduce PADME
Doctors at the UNC School of Medicine, including Mildred Kwan, MD, PhD, and Cincinnati Children’s collaborate to develop an innovative, patient-initiated online platform designed to remove the penicillin allergy label from misdiagnosed pediatric patients. Here’s the scene. Your child appears to be sick. You take their temperature. Fever is over 100. Their throat hurts. You immedi … Read more
GIE Medical Announces First Patient Enrolled in PATENT-E Benign Esophageal Stricture Treatment Study
The large, multicenter randomized controlled clinical trial is evaluating the safety and efficacy of the ProTractX3™ TTS drug coated balloon for the treatment of benign esophageal strictures. News provided by GIE Medical via PRNewswire. MINNEAPOLIS – GIE Medical, a clinical stage company developing solutions for patients suffering from benign stricture(s) of the esophagus or bowe … Read more
Nelson Expresses Concern for Use of Methotrexate in Hand OA Following Clinical Trial
“Many individuals with hand OA have multiple medical comorbidities and polypharmacy, which are important when considering additional treatments, particularly those with modest benefit and potential adverse effects over the long term,” she said.
Dr. Armistead Awarded Eshelman Institute 2023 Therapeutics Grants
The Eshelman Institute works with Carolina faculty who are collaborating with scientists and health care providers both inside and outside UNC-Chapel Hill, including academia, industry and foundations.
Higher Doses of Oral Semaglutide Improves Blood Sugar Control and Weight Loss
A multicenter, randomized, phase 3b trial, done in collaboration with a UNC School of Medicine researcher, found that once-daily oral semaglutide taken at higher doses of 25mg and 50mg improved regulation of blood sugar levels and weight loss compared to the standard 14 mg dose. Diabetes is a progressive disease that affects one’s ability to control blood sugar levels. For many p … Read more
UNC Research Features Dr. Laura Hanson
Laura Hanson has worked for UNC-Chapel Hill for 31 years in a variety of roles, most recently as a professor of geriatric medicine and the medical director of the Department of Medicine’s Palliative Care and Hospice Program. Read about her research journey.
Dr. Sid Smith Ranked Alongside Top Medicine Researchers
Sidney C. Smith, MD, FAHA, FESC, FACP, MACC, professor of medicine, has been ranked #194 for Best Medicine Scientists in the world and #126 in the US by Research.com. Research.com is a leading academic platform for researchers. The ranking is based on D-index (Discipline H-index) metric, which includes papers and citation values for an examined discipline. The ranking includes … Read more