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Category: Research

  • klara-klein-endocrinology-fellow

    Metformin Use Shows No Increase in Gastrointestinal Adverse Events During GLP-1RA Initiation

    A recent study analyzing data from four pivotal clinical trials—LEADER, STEP 2, SUSTAIN 6, and PIONEER 6—evaluated the impact of concomitant metformin use on gastrointestinal adverse events during the initiation and titration of glucagon-like peptide 1 receptor agonists (GLP-1RA). Klara Klein, MD, PhD, assistant professor of medicine in the UNC Division of Endocrinology led the 1 … Read more

  • Removing the Penicillin Allergic Label: Researchers Introduce PADME

    Doctors at the UNC School of Medicine, including Mildred Kwan, MD, PhD, and Cincinnati Children’s collaborate to develop an innovative, patient-initiated online platform designed to remove the penicillin allergy label from misdiagnosed pediatric patients. Here’s the scene. Your child appears to be sick. You take their temperature. Fever is over 100. Their throat hurts. You immedi … Read more

  • GIE Medical Announces First Patient Enrolled in PATENT-E Benign Esophageal Stricture Treatment Study

    The large, multicenter randomized controlled clinical trial is evaluating the safety and efficacy of the ProTractX3™ TTS drug coated balloon for the treatment of benign esophageal strictures. News provided by GIE Medical via PRNewswire. MINNEAPOLIS – GIE Medical, a clinical stage company developing solutions for patients suffering from benign stricture(s) of the esophagus or bowe … Read more

  • Amanda E. Nelson, MD, MSCR, RhMSUS

    Nelson Expresses Concern for Use of Methotrexate in Hand OA Following Clinical Trial

    “Many individuals with hand OA have multiple medical comorbidities and polypharmacy, which are important when considering additional treatments, particularly those with modest benefit and potential adverse effects over the long term,” she said.

  • Paul Armistead, MD, PhD

    Dr. Armistead Awarded Eshelman Institute 2023 Therapeutics Grants

    The Eshelman Institute works with Carolina faculty who are collaborating with scientists and health care providers both inside and outside UNC-Chapel Hill, including academia, industry and foundations.

  • Higher Doses of Oral Semaglutide Improves Blood Sugar Control and Weight Loss

    A multicenter, randomized, phase 3b trial, done in collaboration with a UNC School of Medicine researcher, found that once-daily oral semaglutide taken at higher doses of 25mg and 50mg improved regulation of blood sugar levels and weight loss compared to the standard 14 mg dose. Diabetes is a progressive disease that affects one’s ability to control blood sugar levels. For many p … Read more

  • Dr. Laura Hanson

    UNC Research Features Dr. Laura Hanson

    Laura Hanson has worked for UNC-Chapel Hill for 31 years in a variety of roles, most recently as a professor of geriatric medicine and the medical director of the Department of Medicine’s Palliative Care and Hospice Program. Read about her research journey.

  • sid-smith-library-photo-career-life-story

    Dr. Sid Smith Ranked Alongside Top Medicine Researchers

    Sidney C. Smith, MD, FAHA, FESC, FACP, MACC, professor of medicine, has been ranked #194 for Best Medicine Scientists in the world and #126 in the US by Research.com.   Research.com is a leading academic platform for researchers. The ranking is based on D-index (Discipline H-index) metric, which includes papers and citation values for an examined discipline. The ranking includes … Read more

  • MacNider Building

    UNC-Chapel Hill Receives $70 Million NIH Grant to Build upon a Robust Translational Science Environment

    Nicholas J. Shaheen, MD, MPH, Bozymski-Heizer Distinguished Professor of Medicine in the Division of Gastroenterology and Hepatology, and John Buse, MD, PhD, Verne S. Caviness Distinguished Professor of Medicine in the Division of Endocrinology and Metabolism, are Co-Principal Investigators and Co-Directors of NC TraCS. NC TraCS has secured a seven-year, $70 million Clinical and … Read more

  • Adrian Austin, MD, MSCR

    Dr. Austin Receives Two-Year, $500K Grant from National Institute of Aging

    C. Adrian Austin, MD, MSCR, was awarded a two-year, $500K, grant from the National Institute of Aging for his project, “Development and Assessment of Diagnostic Accuracy of a Telemedicine-Based Delirium Assessment Tool.” The overarching objective of this project is to develop and establish the diagnostic accuracy of a telemedicine- based delirium assessment tool, the TELE-CAM. De … Read more

  • Lone star tick research

    Using Collaboration to Fight a Tricky Tick-Borne Disease

    Alpha-Gal Syndrome, or AGS, is a recently identified tick-borne disease that triggers an allergy to red meat and other products made from mammals, including cheese, gelatin, and medications like heparin. Since its discovery in 2009, cases in the United States alone have risen from 24 to >40,000 people, owing to the geographic spread of the tick populations and the fact that th … Read more

  • TARC Holds Fifth Annual “Research Day”

    Approximately 100 leading researchers and clinicians, research staff and trainees gathered recently to discuss innovative ways to advance research in arthritis, allergy, and autoimmune diseases. Additionally, attendees who couldn’t participate in person attended remotely. Of particular interest this year was keynote speaker and John B. Winfield, MD Visiting Scholar, Ali Ellebedy, … Read more