Research News

Joshua Zeidner, MD Joshua Zeidner, MD, associate professor of medicine and chief of leukemia research at UNC Lineberger, is the corresponding author of a newly published study on a promising treatment approach for acute myeloid leukemia (AML). The early-phase clinical trial, conducted at 12 centers nationwide, tested whether adding the oral menin inhibitor revumenib to … Read more

Drs. Simon Gray (left) and Jeffrey Jensen (right) Jeffrey Jensen, MD, PhD, a hematology/oncology fellow, and Simon Gray, MD, PhD, an assistant professor in the Division of Gastroenterology and Hepatology, received UNC School of Medicine Physician Scientist Training Program awards. Dr. Gray received an Early-Stage Faculty award, and Dr. Jensen received a Resident/Fellowship Award, providing … Read more

John Buse, MD, PhD, Verne S. Caviness Distinguished Professor of Medicine in the Division of Endocrinology & Metabolism, led a study finding 24% of individuals with difficult-to-control type 2 diabetes also present with hypercortisolism (Cushing’s syndrome). This study, entitled CATALYST and published in Diabetes Care, was the largest and most rigorous trial ever conducted to … Read more

Left to right: Amanda E. Nelson, MD, MSCR, RhMSUS; Liubov Arbeeva, MS; Yvonne Golightly, PT, MS, PhD Amanda E. Nelson, MD, MSCR, RhMSUS, professor of medicine in the Division of Rheumatology, Allergy and Immunology, and other Thurston Arthritis Research Center researchers coauthored a study entitled, “Translational genomics of osteoarthritis in 1,962,069 individuals” in Nature. Their … Read more

Saira Sheikh, MD, Linda Coley Sewell Distinguished Professor of Medicine in the UNC Division of Rheumatology, Allergy & Immunology and Director of the Clinical Trials Program at UNC’s Thurston Arthritis Research Center, along with her brother Shehzad Sheikh, MD, PhD, Professor of Medicine in the UNC Division of Gastroenterology & Hepatology, were invited to pitch … Read more

For the first time, investigators are gaining a clearer understanding of what causes drug-induced antineutrophil cytoplasmic autoantibody (ANCA) vasculitis. In a study published in The Journal of Clinical Investigation, researchers from the University of North Carolina (UNC) Department of Medicine and Kidney Center revealed that hydralazine—a drug commonly used to treat high blood pressure—alters the structure … Read more

Stephen Schworer, MD, PhD, assistant professor of medicine in the UNC Division of Rheumatology, Allergy, and Immunology, was recently awarded the American Academy of Allergy, Asthma & Immunology (AAAAI) Foundation Faculty Development Award for his project, “T2-skewed basal cells promote small airway mucus plugging in asthma.” The AAAAI Foundation is dedicated to supporting the development … Read more

People with metastatic cancer who regularly report their symptoms via a home-based electronic monitoring system experienced improved quality of life, clinical outcomes and well-being, as well as fewer emergency department visits than those who didn’t file reports. Both groups had similar overall survival rates, according to University of North Carolina Lineberger Comprehensive Cancer Center researchers … Read more

Dr. Jenny Flythe, Sherin Ismail, Dr. Michele Jonsson-Funk An article by Sherin Ismail-Atta PharmD, PhD, epidemiology graduate student at the UNC Gillings School of Global Public Health and trainee at the UNC Kidney Center, and her mentors, Michele Jonsson-Funk, PhD, Associate Professor of Epidemiology, and Jennifer Flythe, MD, MPH, Professor of Medicine and Chief of … Read more

Colorectal cancer screening is an effective tool for catching the disease early when it’s most treatable, yet it is underutilized in patient populations who receive primary care at federally qualified health centers (FQHC). A new study by researchers at UNC Lineberger Comprehensive Cancer Center demonstrated that a targeted intervention can substantially increase screening rates in … Read more

As 2024 comes to a close, we want to recognize the UNC Department of Medicine faculty ranked on Expertscape in their areas of expertise. Over 40 DOM faculty have been internationally ranked. Expertscape ranks researchers based on the quantity and significance of their published studies in a specific topic, with a focus on their authorship and impact … Read more

Jill Cunnup, Administrative Director for Clinical Research, Kelsey Haywood, Pulmonary Diseases and Critical Care Medicine Research Program Director, Alex Kass, MSN, MBA, RN, CDCES, Caleb Hemphill and Brett Phillips, MA,PMP, CCRP, attended the Society of Research Administrators conference in Chicago. The conference theme, Breaking Barriers: Together Towards Tomorrow, offered a wide range of sessions, workshops, … Read more