Adam Rosenthal, PhD |
| Clinical / Research Focus: During infection individual cells of a bacterial pathogen can co-occur in distinct physiological states. Such phenotypic heterogeneity has been recently reported in landmark virulence processes … Read more |
| Mentors: | Undergraduate Students, Medical Students, Graduate Students |
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AFFILIATIONS: Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Evolutionary Biology, Microbiology, Molecular Biology |
Kent Rossman, PhD |
| Clinical / Research Focus: Our group studies the signaling and structural mechanisms employed by RAS superfamily GTPases to regulate critical cellular processes (e.g., proliferation, motility, morphogenesis and apoptosis) and h … Read more |
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AFFILIATIONS: Surgery |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biomaterials, Biophysics, Cell Biology, Molecular Biology, Molecular Medicine, Pharmacology |
Jude Samulski, PhD |
| Clinical / Research Focus: We are engaged in studying the molecular biology of the human parvovirus adeno-associated virus (AAV) with the intent to using this virus for developing a novel, safe, and efficient delivery system fo … Read more |
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AFFILIATIONS: Pharmacology |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Genetics, Molecular Biology, Virology |
Aziz Sancar, MD, PhD |
| Clinical / Research Focus: We have three main areas of research focus: (1) Nucleotide excision repair: The only known mechanism for the removal of bulky DNA adducts in humans. (2) DNA damage checkpoints: Biochemical pathways t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Molecular Biology |
Greg Scherrer, PharmD, PhD |
| Clinical / Research Focus: The primary mission of my laboratory is to elucidate the mechanisms that underlie pain perception and its modulation by opioids. We investigate the sensory, affective, and cognitive dimensions of pain … Read more |
Jeff Sekelsky, PhD |
| Clinical / Research Focus: Genome instability is a major cause of cancer. We use the model organism Drosophila melanogaster to study maintenance of genome stability, including DNA double-strand break repair, meiotic and mitotic … Read more |
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AFFILIATIONS: Biology, Genetics |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Genetics, Genomics, Molecular Biology |
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AFFILIATIONS: Biology, Center for GI Biology and Disease (CGIBD), Lineberger Cancer Center, Microbiology & Immunology, Neuroscience Center |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Cell Biology, Developmental Biology, Gastrointestinal Biology, Genetics, Genomics, Immunology, Microscopy, Molecular Biology, Quantitative Biology |
Kevin Slep |
| Clinical / Research Focus: Our lab examines cytoskeletal dynamics, the molecules that regulate it and the biological processes it is involved in using live cell imaging, in vitro reconstitution and x-ray crystallography. Of pa … Read more |
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AFFILIATIONS: Biology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Biology, Molecular Biology, Neurobiology, Structural Biology |
Tam Sneddon, PhD, FACMG |
| Clinical / Research Focus: As Director of the Clinical Genomic Analysis (GENYSIS) Core (https://www.med.unc.edu/genysis/), I work with clinical researchers to facilitate bioinformatic analysis, variant classification, an … Read more |
| Mentors: | Undergraduate Students, Medical Students, Graduate Students |
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AFFILIATIONS: Genetics, Pathology & Lab Medicine |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Clinical Informatics, Genetics, Genomics, Molecular Biology, Molecular Medicine |
Philip Spanheimer, MD |
| Clinical / Research Focus: I am a surgical oncologist specializing in breast cancer and sarcoma. I try to bring a patient centered focus to the laboratory to understand disease processes and develop better treatments. Our lab h … Read more |
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AFFILIATIONS: Lineberger Cancer Center, Surgery |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Cell Biology, Cell Signaling, Computational Biology, Genetics, Genomics, Molecular Biology, Surgery, Systems Biology |
Brian D. Strahl, PhD |
| Clinical / Research Focus: Eukaryotic genomes are packaged into the nuclei of cells through the actions of histone proteins. These proteins not only play a role in condensing the genome but are fundamental to establishing and m … Read more |
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AFFILIATIONS: Biochemistry & Biophysics |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Biophysics, Cancer Biology, Cell Biology, Cell Signaling, Chemical Biology, Computational Biology, Epigenetics and Chromatin Biology, Genetics, Genomics, HIV/AIDS, Microbiology, Microscopy, Molecular Biology, Organismal Biology, Stem Cells, Structural Biology |
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AFFILIATIONS: Department of Medicine (DOM) |
CLINICAL/RESEARCH INTERESTS: Aging/Geriatrics, Cell Biology, Imaging, Metabolism, Molecular Biology, Molecular Medicine, Orthopaedics, Stem Cells |





