Category: News

A former graduate student Hung Do will join the National Institute on Drug Abuse at NIH as a Staff Scientist in June 2026. Congratulations!

We invite applications for two Postdoctoral positions in AI‑driven drug discovery and accelerated molecular simulations. This role will support innovative research at the intersection of AI, Computational Biophysics and Chemistry, and Drug Discovery. The successful candidate will contribute to the development of advanced AI tools for virtual screening of critical...

Congratulations to Fu for a first-authored Perspective article published in Biophysical Journal on “Prediction accuracy of ligand binding kinetics“! Abstract Ligand binding kinetics including the binding (kon) and dissociation (koff) rates are critical parameters for drug design. The drug residence time or dissociation rate has been shown to correlate with...

Welcome Linnea Zhang to join Miao Lab as an Undergraduate Researcher!

Congratulations to Keya for a first-authored paper published in The Journal of Physical Chemistry B on “Mechanism of Tethered Agonist Binding to an Adhesion G-Protein-Coupled Receptor“! Abstract Adhesion G-protein-coupled receptors (ADGRs) contain a GPCR autoproteolysis-inducing (GAIN) domain that is proximal to the receptor N-terminus and undergoes autoproteolysis at a highly...

Our recent research published in PNAS has been highlighted by UNC Health News: “UNC Scientists Discover How a Critical Signaling Step Works Inside Cells“: “UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors that many common medicines target. Scientists...

Congratulations to Jinan and Victor for a new paper published in PNAS on “Dissociation kinetics of G proteins from G protein–coupled receptors and effects of allosteric modulation“! Really excited to share this story: The PPI-GaMD method developed earlier by Jinan allowed us to capture the “very slow” G protein dissociation...

Welcome Jinkai Cheng as a new graduate rotation student from the Department of Chemistry in Miao lab!

Welcome Zhenpeng (Alex) Liu to join Miao Lab as an Undergraduate Researcher!

Welcome Minghui Gao as a new graduate rotation student from the Department of Chemistry in Miao lab!