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May: Maternal Mental Health Awareness Month

May 26, 2022

Thomas D’Angelo, M.D.   Invasion is a structure not an event M. Jacqui Alexander is referring to colonialism, which we will definitely get into, but the double meaning is relevant to maternal mental health too. For most of human history(99%?)conception, pregnancy, birth and the postpartum period were communal projects. Hopi communities think about a coming … Read more

Methods for characterizing ovarian and adrenal hormone variability and mood relationships in peripubertal females.

May 6, 2022

Results from the present study (funded by the Foundation of Hope for Research and Treatment of Mental Illness) demonstrated that a substantial proportion of peripubertal females (ages 11-14, within 1 year post-menarche) showed weekly mood changes tied to estrone (57%) and testosterone (37%) flux. This is an important first step in understanding the neurophysiological mechanisms … Read more

The impact of adolescent intermittent ethanol exposure on interneurons and their surrounding perineuronal nets in adulthood

May 6, 2022

Binge drinking is a common pattern of alcohol drinking during adolescence. Using rats, we determined that binge levels of alcohol in adolescence persistently altered perineuronal nets, extracellular structures in the brain, in brain regions important for decision making. This paper adds to a growing body of knowledge around how adolescent binge drinking can be harmful … Read more