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Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife
Results suggest that childhood sexual abuse is associated with significant HPA axis changes that are associated with accelerated epigenetic aging. Implications for biological embedding models of early life adversity and adult outcomes are discussed.
RTICBM-74 is a brain-penetrant CB1 receptor allosteric modulator that reduces alcohol intake in rats
The present works shows that a newly developed negative allosteric modulator of the cannabinoid receptor subtype 1 (CB1) receptor with an excellent pharmacokinetic profile reduces alcohol drinking in rats, suggesting potential therapeutic relevance for the treatment of alcohol use disorder.
Teacher and caregiver perceptions of family engagement in teacher-led task-shifted child mental health care in a low-and-middle-income country.
The current study explored teacher and caregiver perceptions of family engagement within a teacher-led, task-shifted mental health intervention in an LMIC. Primary school teachers from five schools in Darjeeling, India delivered evidence-based, indicated mental health care to children with mental health needs throughout the school day. Barriers included logistical challenges and misconceptions about the programme. … Read more
The Potential Emergence of “Education as Mental Health Therapy” as a Feasible Form of Teacher-Delivered Child Mental Health Care in a Low and Middle Income Country: A Mixed Methods Pragmatic Pilot Study.
We assessed task-shifting children’s mental health care to teachers as a potential approach to improving access to child mental health care. Findings support the feasibility of task-shifting children’s mental health care to classroom teachers in resource-limited schools. These findings support the potential emergence of “education as mental health therapy” (Ed-MH) as a new therapy modality.
UNC Awarded $3.9-million grant to study perimenopausal-onset anhedonia and psychosis with simultaneous PET-MR
Gabriel Dichter (UNC Psychiatry), Crystal Schiller (UNC Psychiatry), and David Lalush (Joint Department of Biomedical Engineering) have been awarded a 5-year $3.9-million grant from the National Institute of Mental Health to use simultaneous positron emission tomography and functional magnetic resonance imaging (PET-MR) to examine the effects of estradiol on reward circuitry functioning in a transdiagnostic … Read more
December: Eating Disorders During the Holidays
Written by Dr. Jean Doak, Clinical Director, UNC Center of Excellence for Eating Disorders (CEED) The holiday season is a time accompanied by celebrations, observances, religious, family, and cultural traditions, and increased time with family and friends. While it can be a time of excitement, anticipation, and joy, it can also be a time … Read more