The psychedelic psilocin suppresses activity of central amygdala corticotropin releasing factor receptor 1 neurons and decreases ethanol drinking in female mice
January 12, 2026
This study reveals that psilocin, the active compound in psychedelic mushrooms, reduces alcohol consumption in female mice by suppressing specific stress-related neurons in the brain. These findings offer new insight into the biological mechanisms that may allow psychedelic therapies to effectively treat alcohol use disorder.
