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A proactive consultation-liaison psychiatry implementation framework for the management of medical and surgical inpatients with psychiatric comorbidities

November 2, 2021

Drs. Asuquo (UNC Gillings School of Public Health), Goodman, Gaynes, and Nakamura propose an adaptation of a collaborative care model for implementation and evaluation of proactive consultation-liaison psychiatry services to improve management of patients with psychiatric conditions who are hospitalized on inpatient medical and surgical services

Impact of patient and clinical characteristics on cognitive changes after allogeneic hematopoietic stem cell transplantation

November 2, 2021

In this longitudinal study of patients hematologic cancers, Drs. Nakamura, Rosenstein, and colleagues identified that cognitive impairment was common over the 6 months following stem cell transplantation. However, cognition incrementally improved among study participants over time and, of importance, more severe disease and aggressive prior treatment did not impede this positive trajectory.

Self-Determination in Autistic Transition-Aged Youth without Intellectual Disability

November 2, 2021

Self-determination refers to an individual’s capacity and opportunities to act as a causal agent in their own lives to make choices, decisions, and set goals. Both depression and executive function skills were related to self-determination capacity in autistic transition-aged youth, highlighting potential intervention targets to facilitate increased self-determination and potentially improved adult outcomes.

Validation of screening tools for common mental health disorders in the methadone maintenance population in Hanoi, Vietnam.

November 2, 2021

We validated the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder screen (GAD-7) and Primary Care PTSD screen for DSM-5 (PC-PTSD-5) in a methadone maintenance therapy (MMT) patient population in Hanoi, Vietnam. The prevalence of CMDs in the MMT population was lower than expected. A lower cut-off score may be considered when screening for CMDs in … Continued

DIP: Natural history model for major depression with incidence and prevalence.

November 2, 2021

We constructed a preliminary model for the natural history of major depression. We determined that the lifetime prevalences are underestimated and the average incidence rates may be underestimated for males. We conclude that recall bias needs to be accounted for in modeling or burden estimates, where the recall bias should increase with age.

Interoception and alcohol: Mechanisms, networks, and implications

November 2, 2021

In this review we discuss interoceptive processes related to alcohol. We cover physiological responses to alcohol, how interoceptive states can impact drinking, and the recruitment of brain networks as informed by clinical research. We also review the molecular and brain circuitry mechanisms of alcohol interoceptive effects as informed by preclinical studies. Lastly, we discuss emerging … Continued